is currently being tested in people with Alzheimer's disease.
Roger Stoll, CEO of Cortex Pharmaceuticals, a neuroscience company focused on innovative drug therapy including their leading ampakine
compound, CX717 which targets various neurological and psychiatric disorders.
Increased net losses in the current year periods reflect development expenses for the AMPAKINE
(R) compound, CX717 and increased preclinical research and development of the AMPAKINE
Unfortunately, the first generation drug faltered in clinical trials but the firm is moving ahead with a more potent ampakine
compounds are a very interesting class of molecules," said Vincent F.
Gary Lynch of the University of California, Irvine, said Sunday the drug called ampakine
CX-516 accelerates signals between brain cells and appears to sharpen the memory significantly.
Specifically, these new AMPAKINE
patents cover a series of compounds including the lead preclinical compounds, CX2007 and CX2076.
Cortex Pharmaceuticals is testing and developing a second-generation class of pharmaceuticals classified as ampakine
family of compounds, numbering approximately 300 to date, target nerve cell connections that exist only in the brain.
The Company is not entitled to any royalties or further payments from Servier's development and commercialization of CX1632, other than reimbursements for certain royalties and milestone payments to the University of California paid by Cortex, but Cortex retains all rights for its remaining AMPAKINE
technology on a worldwide basis.
compounds target and enhance the function of complexes in the brain called the AMPA-type receptors, which are thought to play a role in memory formation.
The MOU also provides Samyang with rights of negotiation to expand its territory into other South East Asian countries, excluding Japan, Taiwan and China, and to include rights to the high impact AMPAKINE
CX1846 as a potential treatment for neurodegenerative diseases.