amoxapine


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amoxapine

 [ah-mok´sah-pēn]
a tricyclic antidepressant of the dibenzoxazepine class; administered orally.

amoxapine

/amox·a·pine/ (ah-mok´sah-pēn) a tricyclic antidepressant of the dibenzoxazepine class.

amoxapine

[əmok′sepin]
a tricyclic antidepressant (secondary amine subclass).
indication It is prescribed in the treatment of mental depression.
contraindications It is used with caution in conditions in which anticholinergics are contraindicated, in seizure disorders, and in cardiovascular disorders. Concomitant administration of monoamine oxidase inhibitors, recent myocardial infarction, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the most serious adverse reactions are sedation and anticholinergic side effects. A variety of GI, cardiovascular, and neurological reactions may also occur. It is involved in many drug interactions.

amoxapine

A tricyclic antidepressant of the dibenzoxazepine class.
 
Adverse effects
Tardive dyskinesia, sedation, postural hypotension, cholinergic effects (e.g., dry mouth, blurred vision, constipation, urinary retention, weight gain), neuroleptic malignant syndrome, cardiovascular effects (EKG, slow AV conduction); withdrawal symptoms accompany abrupt withdrawal.
 
Toxic range
> 500 ng/mL.
 
T1/2
30 hours as metabolite (8-hydroxyamoxipine).
 
Method
HPLC.

amoxapine

Neuropharmacology A tricyclic antidepressant Adverse effects Tardive dyskinesia, sedation, postural hypotension, cholinergic effects—eg dry mouth, blurred vision, constipation, urinary retention, weight gain, neuroleptic malignant syndrome, cardiovascular effects—EKG, slow AV conduction; withdrawal symptoms accompany abrupt withdrawal

amoxapine

A tricyclic antidepressant drug similar to IMIPRAMINE. Overdosage may cause acute kidney failure, convulsions and coma. A brand name is Asendis.

amoxapine (əmok´səpēn),

n brand name: Asendin;
drug class: tricyclic antidepressant;
action: inhibits both norepinephrine and serotonin (5-HT) uptake in brain;
uses: depression.

amoxapine

a tricyclic antidepressant, similar to amitriptyline, used in the treatment of psychogenic dermatoses in dogs and cats.
References in periodicals archive ?
Prolactin stimulating effects of amoxapine and loxapine in psychiatric patients.
Various antidepressant drugs have a piperazine nucleus such as amoxapine, befuraline.
In this group, reboxetine (2 mg) showed the maximum price variation of 900%, while amoxapine (50 mg) showed the minimum price variation of 17.
30 TPM amoxapine, 6 TPM venlafaxine, 6 TPM progunil HCl, 6 TPM CB-2-L-Valine, 0.
Measurement of plasma concentrations: Sample preparation for analysis consisted of adding 300 [micro]L of acetonitrile containing 100 ng/mL amoxapine (100%, Sigma-Aldrich, St Louis, MO, USA), which served as the internal standard, to 100 [micro]L of parrot plasma in a 96-well, 1-mL protein precipitation filter plate (Thermo Scientific, Waltham, MA, USA).
propofol Angina medications Perhexiline, amiodarone, dicthylaminoethoxyhexesterol Anti-arrhythmic Amiodarone Antibiotics Tetracycline, antimycin A Anti-depressants Amitriptyline, amoxapine, citalopram, fluoxetine Anti-psycholies Chlorpromazine, fluphenazine.
The medications were classified as selective serotonin reuptake inhibitors (SSRIs) (citalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline); serotonin norepinephrine reuptake inhibitors (venlafaxine); tricyclics (amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, maprotiline, nortriptyline, protriptyline, and trimipramine); newer and atypical agents (mirtazapine, nefazodone, and trazodone); and monoamine oxidase inhibitors (moclobemide, phenelzine, and tranylcypromine).
Patient Age [greater than Antidepressant or equal to]65 <65 Sertraline 25 50 Paroxetine 10 20 Citalopram * 20 20 Fluoxetine 10 20 Fluvoxamine * 100 100 Amitriptyline NR 50 Desipramine 25 100 Doxepin 30 75 Imipramine 30 75 Nortriptyline 30 75 Protriptyline 15 15 Trimipramine 50 75 Clomipramine 75 75 Trazodone 25 150 Buproprion 50 200 Phenelzine 45 45 Tranylcypromine 20 20 Maprotiline 25 75 Nefazodone 100 200 Venlafaxine 50 75 Mirtazapine 15 15 Amoxapine 50 100 * These antidepressants were not addressed in 1997 Department of Veterans Affairs depression guidelines; minimum daily dosage for these medications derived from expert consensus.
Some of the most frequently prescribed tricyclics are amitriptyline (Elavil, Endep), desipramine (Norpramin), clomipramine (Anafranil), doxepin (Sinequan), imipramine, (Tofranil, Tofranil PM), nortriptyline (Pamelor, Aventyl), amoxapine (Asendin), protriptyline (Vivactil) and trimipramine (Surmontil).
Antidepressants were amitriptyline, bupropion, citalopram, desipramine, doxepin, venlafaxine, imipramine, fluoxetine, paroxetine, trazodone, sertraline, amoxapine, and fluvoxamine.
Klerman (1992) reports that the tricyclic antidepressants matprotiline (Ludiomil) and amoxapine (Asendin) are most likely ineffective for panic disorder.