amorolfine


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amorolfine

A drug used externally in the treatment of TINEA infection of the skin. A brand name is Loceryl.

amorolfine

; Loceryl antifungal agent presented as a nail lacquer for daily topical application for 6 weeks at the early stage of white superficial onychomycosis or where only one or two nails are infected, or used topically in conjunction with systemic antifungal medication in cases with widespread mycotic nail infection

amorolfine

a morpholine derivative with antifungal activity.
References in periodicals archive ?
A combination of amorolfine nail lacquer and oral terbinafine is the most commonly used combination therapy.
It contains a biologically active agent selected from the group consisting of terbinafine, naftifine, amorolfine, butenafine, derivatives thereof, salts thereof, or combinations thereof; a delivery vehicle comprising a non-polymeric crystallization inhibitor that is capable of delaying crystallization of the biologically active agent, and a film-former; a volatile solvent in an amount selected to create a subsaturated solution of said biologically active agent; and water.
Sigurgeirsson and coworkers made the case for up-front combination therapy with amorolfine hydrochloride 5% nail lacquer and oral terbinafine for treating onychomycosis in patients with terbinafine monotherapy lack-of-cure risk factors.
He and his coworkers recently showed that amorolfine nail lacquer applied once every 2 weeks is safe and effective for this purpose (J.
CLEAR the problem directly by painting Curanail 5 per cent Nail Lacquer Amorolfine (pounds 18.
The new product, which contains amorolfine hydrochloride as an active ingredient, can exert beneficial effects with once-a-day dosage.
Approved topical treatments for OM include ciclopirox lacquer (Sanofi-Aventis's Batrafen(R) in EU; Penlac(R) in the US) and amorolfine lacquer (Galderma's Loceryl(R); EU), however, both drugs show low efficacy primarily due to the poor bioavailability in the nail bed.
These results contrast favorably with publicly available results for commercially marketed terbinafine, amorolfine and ciclopirox based formulations.