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amlodipine besylate |
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amlodipine besylate (amlō´dipēn bes´
n brand name: Norvasc;
drug class: calcium channel blocker; action: inhibits calcium ion influx across cell membrane during cardiac depolarization; produces relaxation of coronary vascular smooth muscle and dilates coronary arteries; decreases SA/AV node conduction; uses: hypertension as a single agent or in combination with other antihypertensives, chronic stable angina pectoris, vasospastic angina. amlodipine besylate a long-acting dihydropyridine calcium channel blocking agent, used in the treatment of hypertension.
amlodipine besylate Norvasc Pharmacologic class: Calcium channel blocker Therapeutic class: Antihypertensive Pregnancy risk category C ActionInhibits influx of extracellular calcium ions, thereby decreasing myocardial contractility, relaxing coronary and vascular muscles, and decreasing peripheral resistance AvailabilityTablets: 2.5 mg, 5 mg, 10 mg ⊘Indications and dosages ➣ Essential hypertension, chronic stable angina pectoris, and vasospastic angina (Prinzmetal's angina) Adults: 5 to 10 mg P.O. once daily Dosage adjustment• Hepatic impairment Off-label uses• Pulmonary hypertension Contraindications• Hypersensitivity to drug PrecautionsUse cautiously in: Administration• Be aware that this drug may be given alone or with other drugs to relieve hypertension or angina.
Adverse reactionsCNS: headache, dizziness, drowsiness, light-headedness, fatigue, weakness, lethargy CV: peripheral edema, angina, bradycardia, hypotension, palpitations GI: nausea, abdominal discomfort Musculoskeletal: muscle cramps, muscle pain or inflammation Respiratory: shortness of breath, dyspnea, wheezing Skin: rash, pruritus, urticaria, flushing InteractionsDrug-drug. Beta-adrenergic blockers: increased risk of adverse effects Fentanyl, nitrates, other antihypertensives, quinidine: additive hypotension Drug-behaviors. Acute alcohol ingestion: additive hypotension Patient monitoring☞ Monitor patient for worsening angina. Patient teaching• If patient also uses sublingual nitroglycerin, tell him he can take nitroglycerin as needed for acute angina. amlodipine besylate Norvasc® Cardiology A CCB used to treat HTN and angina pectoris. See ACT, Calcium channel blocker, PRAISE. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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The ASCOT-BPLA trial has specifically demonstrated that a regimen starting with amlodipine besylate is better at reducing total cardiovascular events and procedures, fatal and non-fatal stroke, and the risk of new-onset diabetes. Food and Drug Administration (FDA) for a fixed dose combination of two antihypertensives, the calcium channel blocker (CCB) amlodipine besylate (currently marketed by Pfizer as Norvasc) and the angiotensin receptor blocker (ARB) olmesartan medoxomil, or Benicar. The patient's blood pressure was then controlled with amlodipine besylate, a calcium channel blocker. |
amlodipine besylate |
AMLCG AMLCO AMLCTF AMLD AMLE AMLEOA AMLETS amlexanox amlexanox amlexanox AMLF AMLFC Amli AMLIC AMLICO AMLID AMLIP AMLIPC AMLIS AMLIT AMLL AMLN Amlo Amlodin Amlodipine Amlodipine amlodipine besylate amlodipine besylate and atorvastatin calciumAmlodipine maleate AMLOR AMLP AMLPU AMLR AMLRA AMLRDC AMLRNRMB AMLS AMLSCU AMLSD AMLT AMLTC AMLU AMLV AMM AMM Amma Amma Amma AMMAA Ammah AMMAHLS AMMAL | ||||||||
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