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amitrole

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amitrole, aminotrazole
a nitrothiazole derivative used in the treatment and prevention of histomoniasis of turkeys. Excessive dosage causes infertility and renal and hepatic disease.


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, thionamides, amitrole, and ethylenethiourea) decrease TH synthesis by inhibition of thyroid peroxidase (Capen 1997, 1998; Hill et al.
For five chemicals (amitrole, DDT, dieldrin, PBB, DPH), the same tumors were observed from early and/or adult exposures, although the studies for amitrole, DDT, and dieldrin evaluated the animals only for liver tumors.
(a) The chemicals classified as mutagenic were benzidine, benzo(a)pyrene, DEN, safrole, and vinyl chloride; the chemicals classified as not mutagenic were amitrole, diphenylhydantoin, ethylene thiourea, and polybrominated biphenyls.
 
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