amiodarone-induced thyrotoxicosis

amiodarone-induced thyrotoxicosis

Cardiology Thyroid disease caused by amiodarone, an iodine-rich antiarrhythmic, which occurs in up to ±10% of amiodarone recipients living in areas of moderate iodine deficiency. See Thyrotoxicosis.
Mentioned in ?
References in periodicals archive ?
Amiodarone-induced thyrotoxicosis presenting as hypokalemic periodic paralysis.
4]) in a patient with progressive type II amiodarone-induced thyrotoxicosis (AIT) who was undergoing thyroidectomy.
Amiodarone-induced thyrotoxicosis (AIT) has long posed a challenge to surgeons who attempt to treat it with thyroidectomy in that the very entity that necessitates surgical treatment represents the primary danger associated with surgery.
We present a patient with medically refractory amiodarone-induced thyrotoxicosis after a 2-year history of amiodarone use, resulting in cardiac arrest and encephalopathy.
The relative frequency of amiodarone-induced hypothyroidism (AIH) and amiodarone-induced thyrotoxicosis (AIT) depends on the iodine status of the population.
A near-total thyroidectomy has, however, emerged as an excellent option for amiodarone-induced thyrotoxicosis refractory to medical management.
More recently, perchlorate has been used (alone or in combination with other antithyroid drugs) to treat amiodarone-induced thyrotoxicosis or hypothyroidism, conditions in which underlying thyroid abnormalities are unmasked when the iodine-containing drug amiodarone is given to control cardiac arrhythmia (9).
7) In a significant number of cases, amiodarone-induced thyrotoxicosis responds poorly to medical management, and a total thyroidectomy may need to be considered.
Laroia ST, Zaw KM, Ganti AK, et al: Amiodarone-induced thyrotoxicosis presenting as hypokalemic periodic paralysis.
We describe a case of amiodarone-induced thyrotoxicosis in a 34-year-old man who presented with sudden lower extremity weakness, heat intolerance, and weight loss.
3] levels may also be useful in amiodarone-induced thyrotoxicosis, and in assessing recurrence after antithyroid therapy.
Two mechanisms are responsible for the production of amiodarone-induced thyrotoxicosis (AIT).