aminopeptidase


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Related to aminopeptidase: leucine aminopeptidase

a·mi·no·pep·ti·dase

(ă-mē'nō-pep'ti-dāz),
Enzyme that catalyzes the breakdown of a peptide, removing the amino acyl residue at the amino end of the chain (that is, an n-exopeptidase); found in intestinal secretions.

aminopeptidase

(ə-mē′nō-pĕp′tĭ-dās′, -dāz′, ăm′ə-)
n.
Any of various enzymes that catalyze the hydrolysis of the terminal peptide bond of a polypeptide from the end that contains a free amino group.

aminopeptidase

Any of the hydrolases–enzymes, which catalyze the removal of amino terminal amino acids or dipeptides from a protein or peptide

a·mi·no·pep·ti·dase

(ă-mē'nō-pep'ti-dās)
[EC sub-group 3.4.11] Enzyme catalyzing the breakdown of a peptide, removing the aminoacid at the amino end of the chain (i.e., an exopeptidase); found in intestinal secretions.

aminopeptidase

an enzyme that catalyses the sequential hydrolysis of amino acids in a polypeptide chain from the N-terminal.

aminopeptidase

an enzyme produced by the intestinal mucosa which completes the process of protein digestion by hydrolyzing the amino-terminal amino acids of peptides and some proteins, after the initial breakdown of protein to peptides has already taken place, e.g. the enzyme that removes the methionine coded by the initiation codon AUG.
References in periodicals archive ?
Serum leucine aminopeptidase profile in cancers of gastrointestinal tract with special reference to hepatic metastasis.
chartarum and three control subjects were digested with pronase and leucine aminopeptidase, and the adducts were affinity purified and analyzed by MALDI-TOF MS.
As a leading provider of research reagents, we will be making recombinant Aminopeptidase P protein available for research applications to academic and research institutions.
As the concentration of aminopeptidase I increases, the antibody 15 shows less ability to recover phosphorylated fragments, indicating that phosphorylation site is localized exclusively on N-terminal domain and near the extreme end of the N-terminus.
Proline aminopeptidase as a rapid diagnostic test to confirm bacterial vaginosis.
The session, titled "Beloranib, a Methionine Aminopeptidase 2 Inhibitor, Reduces Body Weight, Plasma Lipids, and Inflammatory State in Obese Women," will be held as part of the "Pharmacology Update" pre-conference session.
The aminopeptidase test (6) was also used to differentiate C.
Tosedostat is an oral, aminopeptidase inhibitor that has demonstrated significant anti-tumor responses in blood related cancers and solid tumors in phase I-II clinical trials.
Ang III and Ang IV are N-terminal degradation products of Ang II that are generated by the activity of aminopeptidase A (19-22).
Lox was best predicted by lymphocyte antigen 6 complex, locus H (Ly6h) (36%), single-stranded interacting protein 1 (36%), and glutamyl aminopeptidase (23%).
L-Leucine-p-nitroanilide, Suc-L-Ala-L-Ala-L-Phe-7-amido-3-methylcoumarin (SAAP-AMC), Aminopeptidase N (APN), arabinosylcytosine, epigallocatechin gallate and phosphoramidon were obtained from Sigma; Hip-L-His-L-Leu was purchased from Bachem; lisinopril was a gift of Schering & Plough (USA); the cell culture media and fetal calf serum (FCS) were obtained from Biochrom; green tea extract (EFLA[R]85942) was obtained from Emil Flachsmann AG (Switzerland).
Tokyo, Japan) has patented cDNA encoding a new aminopeptidase derived from germinated soybeans, a recombinant expression vector containing the DNA , a transformant obtained by the transformation with the expression vector, and a method of producing an aminopeptidase by culturing the transformed product.