aminolevulinic acid


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Related to aminolevulinic acid: porphyria

aminolevulinic acid

 (ALA) [ah-me″no-lev″u-lin´ik]
δ-aminolevulinic acid; a precursor of porphyrins and hemoglobin; serum levels of this acid are elevated in lead poisoning and urinary levels are increased in some porphyrias. The hydrochloride salt is used as a topical photosensitizer in the treatment of nonhyperkeratotic actinic keratoses.

aminolevulinic acid

/ami·no·lev·u·lin·ic ac·id/ (ALA) (-lev″u-lin´ik) δ-aminolevulinic acid; an intermediate in the synthesis of heme; blood and urinary levels are increased in lead poisoning, and urinary levels are increased in some porphyrias. The hydrochloride salt is used as a topical photosensitizer in the treatment of nonhyperkeratotic actinic keratoses.

aminolevulinic acid

a photochemotherapeutic agent.
indication It is used to treat nonhyperkeratotic actinic keratosis of the face and scalp.
contraindication Known hypersensitivity to porphyrins contraindicates this drug's use.
adverse effects Side effects include crusts, hypopigmentation or hyperpigmentation, ulceration, pain, itching, bleeding, and pustules at the site of application.

aminolevulinic acid (ALA)

[am′inōlev′o̅o̅lin′ik]
the aliphatic precursor of heme. It is formed in the body from the condensation of glycine and succinyl coenzyme A and undergoes further condensation to form porphobilinogen. Aminolevulinic acid may be detected in the urine of some patients with porphyria, liver disease, and lead poisoning.

aminolevulinic acid

Oncology A drug used in photodynamic therapy which is absorbed by tumor cells and activated when exposed to light, killing the cells. See Photodynamic therapy.

aminolevulinic acid

see δ-aminolevulinic acid.
References in periodicals archive ?
Porphobilinogen synthase aminolevulinic acid dehydratase) activity in human erythrocytes: reactivation by zinc and dithiothreitol depending on influence of storage.
R]], aminolevulinic acid, and our proprietary Levulan Kerastick formulation together to treat actinic keratoses.
A single-center study of aminolevulinic acid and 417 nm photodynamic therapy in the treatment of moderate to severe acne vulgaris.
It has been shown that applying the photosensitizer aminolevulinic acid topically during a PDT treatment can enhance laser absorption by the skin and destroy the surrounding oil follicles, which inhibits oil production and acne-causing bacteria," said Dr.
Photodynamic therapy, or PDT, is a non-invasive treatment which uses laser or light energy to activate a photosensitizer or photosensitizing agent -- applied topically to the skin prior to treatment -- known as aminolevulinic acid (ALA).
Photodynamic therapy, a treatment that uses the combination of a photosensitizing medication called aminolevulinic acid with laser and light treatment, also targets the oil glands and P.
For example, lead is known to bind to the enzyme aminolevulinic acid dehydratase (ALAD), and the absorption of lead is inversely related to calcium stores and dietary vitamin D intake (Chisolm et al.