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aminolevulinate dehydratase

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aminolevulinate dehydratase
an enzyme involved in the synthesis of heme; abbreviated ALAD. The enzyme is inhibited by lead. In cases of lead poisoning blood levels of the enzyme fall, protoporphyrins and δ-aminolevulinic acid accumulate in the blood. The acid spills over into the urine thus forming the basis of the tests for lead poisoning. Called also porphobilinogen synthase.


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