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aminoacylation

   Also found in: Wikipedia 0.01 sec.
aminoacylation
a two stage process whereby amino acids are 'activated' in order to be incorporated into proteins; energy in the form of ATP is required and one of a family of 20 aminoacyl-tRNA synthetases, one specific for each amino acid, links the carboxyl group of the amino acid to either the 2′- or 3′-hydroxyl group of the ribose unit at the 3′-end of tRNA.


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Decreased aminoacylation of mutant tRNAs in MELAS but not in MERRF patients.
Section II The RNA World 10:00 RIBOZYME-CATALYZED AMINOACYLATION FROM ACETYL COA Na Li* and Faqing Huang, University of Southern Mississippi, Hattiesburg, MS 39406 According to the RNA world hypothesis, the evolution of coded protein synthesis was a critical step in the transition from the RNA world to our contemporary biological systems.
A tRNA aminoacylation system for non-natural amino acids based on a programmable ribozyme.
 
 
 
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