aminoacylation


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aminoacylation

The attachment of an amino acid to the acceptor arm of a TRANSFER RNA molecule. This is an essential step in the synthesis of a protein. The attachment is brought about by the appropriate AMINOACYL-TRNA SYNTHETASE.

aminoacylation

a two stage process whereby amino acids are 'activated' in order to be incorporated into proteins; energy in the form of ATP is required and one of a family of 20 aminoacyl-tRNA synthetases, one specific for each amino acid, links the carboxyl group of the amino acid to either the 2′- or 3′-hydroxyl group of the ribose unit at the 3′-end of tRNA.
References in periodicals archive ?
coli, it has been shown that when the rate of tRNA aminoacylation does not meet the demands of protein synthesis, the ribosome associated RelA is activated (1).
10:00 RIBOZYME-CATALYZED AMINOACYLATION FROM ACETYL COA
Leu(UUR)] mutation causes aminoacylation deficiency and concomitant reduced association of mRNA with ribosomes.