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amikacin |
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amikacin /am·i·ka·cin/ (am″ĭ-ka´sin) a semisynthetic aminoglycoside antibiotic derived from kanamycin, used as the sulfate salt in the treatment of a wide range of infections due to aerobic gram-negative bacilli. amikacin Therapeutics The broadest of the broad-spectrum aminoglycosides, which is resistant to aminoglycoside-inactivating enzymes Indications Nosocomial gram-negative bacterial infections–eg, with Enterobacter spp,
Klebsiella spp, Proteus spp, Pseudomonas aeruginosa, Serratia spp, E coli, possibly MAC Adverse effects Ototoxicity, nephrotox-icity How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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coli
CO strain was also resistant to gentamicin, kanamycin, chloramphenicol,
tetracycline, and trimethoprim-sulfamethoxazole; intermediately
susceptible to nalidixic acid and tobramycin; and remained susceptible
to amikacin, netilmicin, ofloxacin, and ciprofloxacin. (7) It has been suggested that patients who do not
respond to this strategy should be placed on amikacin therapy and that
IJV ligation be employed only after more conservative therapy has been
attempted (8) or if evidence of septic emboli appears. Other products in the
proprietary Nektar pipeline include inhaled amikacin for adjunctive
treatment of gram negative pneumonia in mechanically ventilated
patients; and two PEGylated products not yet disclosed for treating
oncology and pain indications. |
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