amikacin


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amikacin

 [am″ĭ-ka´sin]
a semisynthetic aminoglycoside antibiotic derived from kanamycin, used as the sulfate salt in the treatment of a wide range of infections due to susceptible gram-negative organisms.

amikacin

/am·i·ka·cin/ (am″ĭ-ka´sin) a semisynthetic aminoglycoside antibiotic derived from kanamycin, used as the sulfate salt in the treatment of a wide range of infections due to aerobic gram-negative bacilli.

amikacin

Therapeutics The broadest of the broad-spectrum aminoglycosides, which is resistant to aminoglycoside-inactivating enzymes Indications Nosocomial gram-negative bacterial infections–eg, with Enterobacter spp, Klebsiella spp, Proteus spp, Pseudomonas aeruginosa, Serratia spp, E coli, possibly MAC Adverse effects Ototoxicity, nephrotox-icity

amikacin

An antibiotic drug, one of the AMINOGLYCOSIDES. The drug is on the WHO official list. A brand name is Amikin.
References in periodicals archive ?
An empiric regimen for RGM consisting of intravenous cefoxitin and amikacin and oral clarithromycin and moxifloxacin were administered.
Food and Drug Administration (FDA) has granted qualified infectious disease product (QIDP) designation to two Bayer investigational agents, Amikacin Inhale and Ciprofloxacin Dry Powder for Inhalation (DPI).
According to a new market report published by Transparency Market Research "Pipeline Analysis of Hospital Acquired Pneumonia Drugs Market (Tedizolid Phosphate, Ceftolozane/Tazobactam, Ceftazidime/Avibactam, Amikacin Inhale, Plazomicin, and Synflorix) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2014 - 2020" six phase III drugs would generate total revenue of USD 3.
Then the dogs were treated based on clinical diagnosis with ciprofloxacin and amikacin drops.
We conducted a prospective study of 105 patients who were receiving a potentially ototoxic drug--either gentamicin, amikacin, or cisplatin--to assess the value of ultrahigh-frequency audiometry in detecting systemic drug-induced hearing loss.
According to Qaffari, the outcomes of the research work are as follows: preparation of inhalation dosage form of amikacin (nanoparticles), lowered toxicity of the drug in kidneys, increased pulmonary concentration of the drug, design of a more effective drug which decreases required injection times, preparation of noninvasive form of amikacin and improved chance of curing pulmonary infections like cystic fibrosis.
In the same form synergism between chlorpromazine and kanamycin, amikacin and tobramycin was observed, indicating the involvement of an efflux system.
Proceeds from the financing will enable Transave to deliver Phase II proof of concept data for our lead clinical compound, ARIKACE(tm) (liposomal amikacin for inhalation).
Thus, in the presence of neomycin, gentamicin, tobramycin, amikacin, streptomycin, or kanamycin, the urine control protein value was falsely increased by 197%, 130%, 85%, 18%, 36%, and 70%, respectively (n = 4; CV <10%).
NKTR-061 (inhaled amikacin) is currently being tested to further evaluate the safety, tolerability, and deep lung concentrations of amikacin formulated for inhalation for the adjunctive treatment of gram-negative pneumonia in ventilated patients diagnosed with hospital or ventilator associated pneumonia.
Amikacin, injectable solution 250 mg / ml vial or ampule 2 ml