amidase


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am·i·dase

(am'i-dās),
An enzyme that catalyzes the hydrolysis of monocarboxylic amides to free acid plus NH3; ω-amidase acts on amides such as α-ketoglutaramic acid and α-ketosuccinamic acid.

amidase

/am·i·dase/ (am´ĭ-dās)
1. any of a group of enzymes that catalyze the cleavage of carbon–nitrogen bonds in amides.
2. an enzyme that catalyzes the cleavage of the carbon–nitrogen bond of a monocarboxylic acid amide to form a monocarboxylic acid and ammonia.

amidase

[am′i·dās]
1 an enzyme that catalyzes the formation of a monocarboxylic acid and ammonia by hydrolytic cleavage of the C─N bond of a monocarboxylic acid amide.
2 a term used in the recommended and trivial names of some hydrolases acting on amides, particularly those acting on linear amides.

amidase

(am′ĭ-dās″) [ amide + -ase]
An enzyme that catalyzes the hydrolysis of amides; a deamidizing enzyme.
References in periodicals archive ?
This suggests that any CDEPA or CMEPA produced in this time was either not being metabolized to the corresponding aniline by the aryl amidase or metabolized so slowly as to preclude detection.
Inhibition of the amidase enzyme, which has been identified in M.
12) Peptidases break down proteins, amidases break amide bonds, and lysozymes break down peptidoglycans found in cell walls of bacteria.
The grant will enable ThermoGen to develop a toolbox of stable amidases to expand their current technology platform, which helps the company's clients synthesize biologically active compounds efficiently, economically and in an environmentally friendly manner.
He has been Professor for Biotechnology at the TU Hamburg-Harburg, Germany, since 1986, focusing his research on fundamentals of equilibrium and kinetically controlled reactions catalyzed by free and immobilized hydrolases, the production, post-translational processing and purification of penicillin amidases and serine peptidases by affinity chromatography, as well as fundamentals of mass transfer in chromatography and enzyme technology.
This toolbox is constantly expanding and includes all major classes of catalytic activities that are relevant for fine chemistry such as esterases, nitrilases, nitrile hydratases, amidases, epoxyde hydrolases, oxydo-reductases and many other ones" said Daniel Dupret, Chairman and CEO of Proteus.