ameroid constrictor

ameroid constrictor

a device for gradual occlusion of blood flow used on extrahepatic portosysemic vascular shunts. There is an inner ring of casein, which swells as it absorbs tissue fluid, inside a ring of stainless steel.
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An ameroid constrictor was surgically placed around one of the major coronary arteries of each pig to stimulate the effect of human chronic coronary artery disease.
In a subsequent study designed to examine the stimulation of new blood flow in the ischemic heart of Yorkshire miniswine, the effects of single treatment of nicotine using the ameroid constrictor model demonstrated significant evidence of angiogenesis, showing DNA synthesis indicative of dividing endothelial and smooth muscle cells and compensatory vessel collateralization using various staining methods.
Approximately six weeks prior to the injection procedure, each of the pigs underwent surgery to implant an ameroid constrictor around one of their major coronary arteries.