The chapters on the liver address immunology, inborn errors of metabolism, hepatitis, nonalcoholic fatty liver disease, alcoholic liver disease, primary sclerosing cholangitis, primary biliary cirrhosis, autoimmune hepatitis, amebic liver abscess
, pyogenic liver abscess, hydatid cysts, leptospirosis, cirrhosis, ascites, hepatic encephalopathy, hepatocellular carcinoma, portal hypertension, hepatorenal syndrome, drug-induced liver injury, acute liver failure, biliary atresia, liver diseases in pregnancy, liver transplantation, gallstone disease, cholangiocarcinoma, acute and chronic pancreatitis, and pancreatic cancer, including information on pathogenesis, epidemiology, etiology, diagnosis, clinical features, treatment, differential diagnosis, prognosis, and other aspects.
The combined prevalence of amebic colitis and amebic liver abscess
is estimated at 40 to 50 million cases annually worldwide, resulting in 40,000 to100,000 deaths every year.
Tinidazole, an antiprotozoal agent that has been used in other countries for more than 25 years, also received Food and Drug Administration approval for treating giardiasis, intestinal amebiasis, and amebic liver abscess