amber mutation


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am·ber mu·ta·tion

a mutation that results in the formation of the codon UAG, which results in the premature termination of a polypeptide chain. Compare: suppressor mutation.

amber mutation

Etymology: Ar, anbar, ambergris
a genetic alteration that causes the synthesis of a polypeptide chain to terminate prematurely because the triplet of nucleotides that normally codes for the next amino acid in the chain becomes uracil-adenine-guanine, the sequence that signals the end of the chain. This is one of three possible nonsense mutations.See also ochre mutation,opal mutation.

amber mutation

A mutation that creates an AMBER CODON.
References in periodicals archive ?
If the translation molecules corrected the amber mutation with a natural amino acid, the bacteria would make barnase and die.