amantadine


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amantadine

 [ah-man´tah-dēn]
an antiviral compound used as the hydrochloride salt to treat influenza A; also used as an antidyskinetic in the treatment of parkinsonism and drug-induced extrapyramidal reactions.

amantadine

/aman·ta·dine/ (ah-man´tah-dēn) an antiviral compound used as the hydrochloride salt to treat influenza A; also used as an antidyskinetic in the treatment of parkinsonism and drug-induced extrapyramidal reactions.

amantadine

(ə-măn′tə-dēn′)
n.
A drug, C10H17, used in its hydrochloride form as an antiviral agent and treatment for Parkinson's disease.

amantadine

An antiviral agent that prevents the release of viral nucleic acid into the host cells, which is most effective against influenza virus; in parkinsonism, amantadine increases presynaptic dopamine release, blocks dopamine reuptake into the presynaptic neurons and has anticholinergic effects.
 
Adverse effects
Nausea, vertigo, confusion, hallucinations, anxiety, restlessness, depression, irritability, peripheral oedema, orthostatic hypotension, psychotic reaction.

Amantadine™

Therapeutics An antiviral that prevents the release of viral nucleic acid into the host cells, which is most effective against influenza virus; in parkinsonism, amantadine ↑ presynaptic dopamine release, blocks dopamine reuptake into the presynaptic neurons, and has anticholinergic effects Adverse effects Nausea, vertigo, confusion, hallucinations, anxiety, restlessness, depression, irritability, peripheral edema, orthostatic hypotension, psychotic reaction

amantadine

An antiviral drug, also used to treat PARKINSON'S DISEASE. Brand names are Lysovir and Symmetrel.

amantadine (əman´tidēn),

n an antiviral that prevents uncoating and replication of the influenza A virus; most effectively used in the early stages of exposure.
References in periodicals archive ?
Amantadine has been used as an antiparkinsonian drug since 1969.
The alert recommended against the use of amantadine or rimantadine for treatment or prophylaxis of influenza A infections in the United States for the rest of the 2005-2006 flu season.
Rimantadine is a derivative of the drug amantadine.
Although they believed they had cured the woman's disease with amantadine sulfate, she later suffered a relapse, thought to be caused by too-rapid lowering of her amantadine dosage.
Because amantadine must be taken daily during the six- to 12-week peak flu season, and since it does not prevent all flu illnesses, the vaccine is a better choice for those who can take it.
A drug called amantadine also can be used to help prevent flu.
There is one prescription antiviral medicine, amantadine hydrochloride, that can shorten the course of one serious form of influenza if taken shortly after its onset.
The company also said it has launched Amantadine HCI brand equivalent to Symmetrel, a registered trademark of Endo Pharmaceuticals, Inc.
the subject of the agreement is medicines containing the active substance amantadine in an oral dosage form.
com)-- Bioo Scientific now offers the MaxSignal[R] Amantadine ELISA Test Kit for the detection of amantadine residues in meat (chicken, beef and pork).
There were used three different concentrations (2%, 4% and 8%) of each of amantadine HCl, extracts of fresh leaves of opuntia herb, papaya and dried powdered leaves of green tea in distilled water and were evaluated for their antiviral activity, by injecting through chorioallantoic sac route into 10 days old live embryonated broiler chicken eggs.
Clinical trials have documented that amantadine hydrochloride [4,5,6,8,13] and its analog rimantadine hydrochloride [3,5,10,13,12] are effective drugs for the prophylaxis and treatment of influenza A virus infection.