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amantadine

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amantadine /aman·ta·dine/ (ah-man´tah-den) an antiviral compound used as the hydrochloride salt to treat influenza A; also used as an antidyskinetic in the treatment of parkinsonism and drug-induced extrapyramidal reactions.
amantadine (man´tidēn),
n an antiviral that prevents uncoating and replication of the influenza A virus; most effectively used in the early stages of exposure.
Amantadine™ Therapeutics An antiviral that prevents the release of viral nucleic acid into the host cells, which is most effective against influenza virus; in parkinsonism, amantadine ↑ presynaptic dopamine release, blocks dopamine reuptake into the presynaptic neurons, and has anticholinergic effects Adverse effects Nausea, vertigo, confusion, hallucinations, anxiety, restlessness, depression, irritability, peripheral edema, orthostatic hypotension, psychotic reaction


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If taken early, the antiviral agents amantadine and rimantadine are effective in reducing the severity of influenza A, while zanamivir and oseltamivir are effective in reducing the severity of both influenza A and B.
PACKED ERS DIVERT PATIENTS FLU CAUSES 57 PERCENT TO CLOSE TO TRAFFIC by Daily News (Los Angeles, CA)
The M2 blocker amantadine is widely used and available without a prescription in some countries, including China, note Yi Guan and Honglin then, both of the University of Hong Kong and Shantou University Medical College in China.
Falling influence: influenza fighters have limited effects by Harder, B. / Science News
NMDA receptor-mediated glutamate toxicity of cultured cerebellar, cortical and mesen-cephalic neurons: Neuroprotective properties of amantadine and memantine.
Pharmacologic manipulation of the labyrinth with novel and ... by Water, Thomas R. Van De / Ear, Nose and Throat Journal
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