altretamine /al·tret·amine/ (al-tret´ah-mēn) an antineoplastic agent used in the palliative treatment of ovarian cancer.
altretamine,
altretamine [al-tret´ah-mēn]
altretamine (altret´
mēn´),
altretamine
altretamine,
an antineoplastic agent.
indications It is used for the palliative treatment of recurrent, persistent ovarian cancer after induction therapy agent.
contraindications< Known hypersensitivity to this drug, severe bone marrow depression, severe neurologic toxicity, and pregnancy prohibit its use.
adverse effects Among the more serious adverse reactions are hepatic toxicity, leukopenia, thrombocytopenia, and anemia.
altretamine [al-tret´ah-mēn]
an antineoplastic agent used in the palliative treatment of ovarian carcinoma. It is structurally related to an alkylating agent but does not act as one; its exact mechanism is unknown. Administered orally.
altretamine (altret´
mēn´),n brand name: Hexalen;
drug class: antineoplastic;
action: products of metabolism interact with tissue macromolecules, including DNA, which may be responsible for cytotoxicity;
uses: palliative treatment of recurrent, persistent ovarian cancer.
drug class: antineoplastic;
action: products of metabolism interact with tissue macromolecules, including DNA, which may be responsible for cytotoxicity;
uses: palliative treatment of recurrent, persistent ovarian cancer.
altretamine
an antineoplastic agent, similar to tretamine.
altretamine
Hexalen Oncology An alkylating anticancer agent. See Chemotherapy.
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