alprostadil


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Related to alprostadil: papaverine

alprostadil

 [al-pros´tah-dil]
name for prostaglandin E1 when used pharmaceutically as a vasodilator and platelet aggregation inhibitor; used for treatment of patent ductus arteriosus and for diagnosis and treatment of impotence.

al·pros·ta·dil

(al-pros'tă-dil),
A vasodilator used for palliative therapy to maintain patency of the ductus arteriosus in neonates with congenital heart defects temporarily.
Synonym(s): prostaglandin E1

alprostadil

/al·pros·ta·dil/ (al-pros´tah-dil) name for prostaglandin E when used pharmaceutically as a vasodilator and platelet aggregation inhibitor; used for the treatment of patent ductus arteriosus and the diagnosis and treatment of impotence.

alprostadil

(ăl-prŏs′tə-dĭl)
n.
A prostaglandin drug, C20H34O5, that acts as a vasodilator and is used in suppository or injectable form to treat erectile dysfunction.

alprostadil

a proprietary form of prostaglandin E1 used to treat impotence and (temporarily) to maintain the patency of the ductus arteriosus in certain neonates.
indication It is recommended as palliative therapy for neonates awaiting surgery to correct congenital cardiac anomalies, such as tetralogy of Fallot and tricuspid atresia.
contraindications It is contraindicated in respiratory distress syndrome and in cases of known hypersensitivity. This drug is contraindicated in pregnant patients.
adverse effects The most common adverse effects are apnea, fever, seizures, cerebral bleeding, flushing, bradycardia, and hypertension.

alprostadil

Urology A formulation of PGE-1 which relaxes the corpus cavernosum, allowing engorging during erection. See Erectile dysfunction, Orgasm.

alprostadil

A PROSTAGLANDIN drug used by penile injection for the treatment of impotence. An erection lasting for two or three hours is commonly achieved, but sales of alprostadil may be adversely affected by the development of drugs such as VIAGRA. Brand names are Caverject, Muse, and Viridal Duo.

Alprostadil

A smooth muscle relaxant sometimes injected into the penis or applied to the urethral opening to treat impotence.
Mentioned in: Impotence

al·pros·ta·dil

(al-pros'tă-dil)
A vasodilator used for palliative therapy to maintain patency of the ductus arteriosus in neonates with congenital heart defects temporarily.
Synonym(s): prostaglandin E1.

alprostadil (alpros´tədil´),

n brand name: Caverject;
drug class: naturally occurring prostaglandin;
action: induces erection by relaxation of trabecular smooth muscle and by dilation of cavernosal arteries;
uses: treatment of erectile dysfunction caused by neurogenic, vasculogenic, psychogenetic, or mixed etiology.
References in periodicals archive ?
Developed in America, MUSE (Medicated Urethral System for Erection) consists of alprostadil in the form of a small pellet delivered directly into the male urethra by a urethral stick - so there are no needles.
Self reports were begun at 5 minutes after alprostadil application, and at 15-minute increments.
President and Chief Executive Officer of NexMed, stated, "Given the disease characteristics, Raynaud's syndrome is an appealing product opportunity for us and one that we believe can benefit strongly from the active ingredient in Vitaros, which is alprostadil, or prostaglandin E1 (PGE1), a potent vasodilator.
Presentation Title: Enhanced effects of specially formulated topical alprostadil cream by a continuous dosing remedy for the treatment of female sexual arousal disorder (FSAD) in a double-blind, multicenter, randomized, and placebo-controlled clinical trial.
Because ALIBRA consists of a single, fixed combination of alprostadil and prazosin HCl, "in office" dosing should not be necessary.
Nasdaq: NEXM), a specialty CRO with a pipeline of products based on the NexACT([R]) technology, today announced results from a pre-clinical study showing that Vitaros([R]), the Company's NexACT-based alprostadil product, significantly promoted healing of deep tissue wounds.
June 21, 2005, 1:00 PM - 4:00 PM Poster Presentation: The Efficacy and Safety Of Alprostadil Cream (Alprox-TD) In Male Patients with Mild to Severe Erectile Dysfunction - U.
The Femprox product incorporates the company's NexACT transdermal penetration enhancing technology with alprostadil, a drug recognized for treating male erectile dysfunction, commonly known as impotence.
NexMed's pipeline includes a late stage terbinafine treatment for onychomycosis, a late stage alprostadil treatment for erectile dysfunction, a P 2 alprostadil treatment for female sexual arousal disorder, and an early stage treatment for psoriasis.
ALISTA is an investigational proprietary formulation of alprostadil applied locally to the female genitalia in Phase 3 clinical trials.
The Company is also developing Femprox(R), a topical formulation that incorporates alprostadil with the NexACT(TM) technology for the treatment of Female Sexual Arousal Disorder.
MUSE should not be used by men who have sickle cell anemia or trait, leukemia or tumor of the bone marrow, allergy to alprostadil (the active ingredient in MUSE), or abnormal penile anatomy.