alphafetoprotein


Also found in: Dictionary.

alphafetoprotein

A protein synthesized in the fetal liver and intestine and present in fetal blood and in the uterine fluid. Raised levels may indicate that the fetus has SPINA BIFIDA or ANENCEPHALY and further investigation becomes urgent. Alphafetoprotein is also produced by certain malignant tumours and its estimation is sometimes used as a marker for the diagnosis of these tumours or their recurrence.
References in periodicals archive ?
Immunohistochemical evaluation of canine primary liver carcinomas: Distribution of alphafetoprotein, carcinoembryonic antigen, keratins and vimentin.
Seppala, "Comparison of Amniotic Fluid and Maternal Serum AlphaFetoprotein Levels in the Early Antenatal Diagnosis of Spina Bifida and Anencephaly, The Lancet, I:429, 1974.
In the second case, results of several different tests, including maternal serum alphafetoprotein (MSAFP), ultrasound, and amniocentesis, are inconsistent but suggest a small neural tube defect.
staining methods for detection of alphafetoprotein binding on
Two-site sandwich enzyme immunoassay with monoclonal antibodies to human alphafetoprotein.
Either ultrasound or maternal serum alphafetoprotein (MSAFP) measurements will identify nearly all anencephalic fetuses tested during the second trimester.
Hepatoma-specific' alphafetoprotein may permit preclinical diagnosis of malignant change in patients with chronic liver disease.
Maternal and fetal alphafetoprotein (AFP) levels at term.
Prasad also led the development and commercialization of recombinant human erythropoietin, recombinant streptokinase, and alphafetoprotein diagnostic kit, as well as helped develop technology for the production of recombinant human insulin.