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alpha2-macroglobulin

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alpha2-macroglobulin /al·pha2-mac·ro·glob·u·lin/ (al´fah mak´ro-glob″u-lin) α.
macroglobulin
immunoglobulin M, an antibody protein (globulin) of molecular weight in the range of 1,000,000.
α2-macroglobulin
a glycoprotein that inhibits proteolytic enzymes. Increased levels are seen in diabetes mellitus and diseases of the liver and kidney.
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Alpha2-macroglobulin Alpha2-macroglobulin (AMG) is similar to AAT and most other proteinase inhibitors, except that it is a very large molecule, approximately 750 kD as compared, for example, to antithromin III (only 65 kD).
Plasma proteins as biomarkers: acute phase proteins by Steinert, Don / FOCUS: Journal for Respiratory Care & Sleep Medicine
Chodorowska G, Wojnowska D, Juszkiewicz-Borowiec M: C-reactive protein and alpha2-macroglobulin plasma activity in medium-severe and severe psoriasis.
Investigation of serum leptin levels in psoriatic ... by Gonul, Turkan; Basak, Pinar Yuksel; Kara, Yusuf; Akkaya, Vahide Baysal; Vural, Huseyin / Archives of the Turkish Dermatology and Venerology
They are believed to act by inhibiting fibroblast growth and decreasing alpha2-macroglobulin levels, leading to collagen degradation.
Combined therapy in the treatment of auricular keloids by Oberman, James P. / Ear, Nose and Throat Journal
 
 
 
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