Alpha2-macroglobulin | definition of alpha2-macroglobulin by Medical dictionary
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alpha2-macroglobulin /al·pha2-mac·ro·glob·u·lin/ (al´fah mak´ro-glob″u-lin) α.
immunoglobulin M, an antibody protein (globulin) of molecular weight in the range of 1,000,000.
a glycoprotein that inhibits proteolytic enzymes. Increased levels are seen in diabetes mellitus and diseases of the liver and kidney.
References in periodicals archive
They are believed to act by inhibiting fibroblast growth and decreasing alpha2-macroglobulin
levels, leading to collagen degradation.
Characterization and immunological determination of the complex between prostate-specific antigen and alpha2-macroglobulin
SynerVax(TM) adjuvant, Synergy Vaccines' proprietary vaccine adjuvant, is based on the plasma protein alpha2-Macroglobulin
and was developed at DUMC by Dr.