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AMACRAlpha-Methylacyl coenzyme A racemase. An enzyme involved in beta-oxidation of branched-chain fatty acids, the gene for which is overexpressed in certain cancers, in particular prostate.
An antibody that is primarily used in histopathology to stain tissues suspected of representing carcinoma of the prostate gland. Its presence substantiates the diagnosis. AMACR is also present in some colonic and some kidney cancer specimens.