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alpha helix
(redirected from alpha-helical)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
alpha helix
n.
The helical form, turned in a right-handed direction, of many proteins.

helix [he´liks] (pl. he´lices, helixes) (Gr.)
1. a winding structure; see also coil and spiral.
2. the superior and posterior free margin of the pinna of the ear.
α-helix (alpha helix) the complex structural arrangement of parts of protein molecules in which a single polypeptide chain forms a right-handed helix.
double helix (Watson-Crick helix) the structure of deoxyribonucleic acid (DNA), consisting of two coiled chains, each of which contains information completely specifying the other chain.


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The five domains include 1) a signal peptide, 2) an alpha-helical charged domain (amino acids 1-288), 3) a proline-rich region (amino acids 289-370), 4) a choline-binding domain consisting of 9 to 10 twenty-amino-acid repeats (amino acid 371-571), and 5) a C-terminal 17-amino-acid tail (amino acids 572-589).
a molecular biologist at the University of California, Berkeley, and his colleagues have used the alpha-helical strands of proteins to engineer a benzene-sensitive switch.
About Stapled Peptides AILERON's Stapled Peptides are synthetically locked, or 'stapled', into an alpha-helical shape with an optimized cross-linking chemistry to mimic the structure found at the interface of many protein-protein interactions.
 
 
 
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