alpha blocker


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alpha blocker

An agent that blocks activity at the alpha-adrenergic receptors, which are used as second-line antihypertensives. Alpha blockers provide symptomatic relief for benign prostate hypertrophy.

Examples
Doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin).
 
Side effects
Dizziness, headache, weakness, nasal congestion, fluid retention, drowsiness.
References in periodicals archive ?
Patients in whom alpha blockers were administered due to the growth of postoperative adenoma and who had been operated on due to urethral stricture, bladder neck contracture or a growing adenoma were also noted and recorded.
In our study, we investigate the predictability of MET success with alpha blockers based on the HU and HD values measured by CT for distal ureteral stones.
17) In our study, spontaneous stone passage in the group treated with alpha blockers and diclofenac sodium was higher than the groups treated with diclofenac sodium only or diclofenac sodium and prednisolone.
Evidence from subsequent analyses of ALLHAT and other clinical outcome trials confirm that neither alpha blockers, angiotensin-converting enzyme inhibitors, nor calcium channel blockers surpass thiazide-type diuretics (at appropriate dosage) as initial therapy for reduction of cardiovascular or renal risk," the authors wrote.
Retrograde ejaculation, or an orgasm with reduced semen, is an expected and reversible effect of selective alpha blockers and thought to be a direct reflection of the product's selective binding properties.
Alpha blockers have been noted to effect cholesterol levels (decrease in total cholesterol, LDL, and triglycerides; increase in HDL).
Finasteride monotherapy maintains stable lower urinary tract symptoms in men with benign prostatic hyperplasia following cessation of alpha blockers.
A provisional diagnosis of pheochromocytoma was done and he started on alpha blockers.
Finasteride monotherapy maintains stable lower urinary tract symptoms in men with BPH following cessation of alpha blockers.
First-generation alpha blockers are nonselective with regard to alpha 1 adrenoreceptor subtypes and, as a result, have been associated with orthostatic hypotension," said Leonard S.