alloxan diabetes

al·lox·an di·a·be·tes

experimental diabetes mellitus produced in animals by the administration of alloxan, which damages the insulin-producing islet cells of the pancreas.

alloxan diabetes

An experimental model for type-1 diabetes induced by administration of alloxan, a toxic glucose analogue, which in the presence of intracellular thiols generates reactive oxygen species that selectively destroy pancreatic beta cells.
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References in periodicals archive ?
Effect of alloxan diabetes, starvation and refeeding on glycolytic kinase activities in rat epididymal adipose tissue.
The Pathological Features of Alloxan Diabetes in Beagle Dogs.
Effects of sodium--orthovanadate and Trigonella foenumgraecum seeds on hepatic and renal lipogenic enzymes and lipid profile during alloxan diabetes.
Effect of Vinca rosea extracts in treatment of alloxan diabetes in male albino rats.
On the other hand, oxidative phosphorylation functions; the activity of NADH dehydrogenase and succinate dehydrogenase in respiratory chain of liver mitochondria were normalized in rats with alloxan diabetes after oral administration of ecdysterone (Tashmukhamedova et al.