| Dictionary, Encyclopedia and Thesaurus - The Free Dictionary 1,763,512,613 visitors served. |
|
Dictionary/ thesaurus | Medical dictionary | Legal dictionary | Financial dictionary | Acronyms | Idioms | Encyclopedia | Wikipedia encyclopedia | ? |
allosteric |
Also found in: Dictionary/thesaurus, Wikipedia | 0.03 sec. |
|
allosteric /al·lo·ster·ic/ (al″o-ster´ik) pertaining to allostery. allosteric pertaining to an effect on the biological function of a protein, produced by a compound not directly involved in that function (an allosteric effector) or to regulation of an enzyme involving cooperativity between multiple binding sites (allosteric sites). allosteric enzymes any enzymes containing an allosteric site, where effector molecules can bind to increase or decrease the rate of reaction, in addition to an active site for substrate binding. Allosteric enzymes exhibit sigmoidal rather than Michaelis-Menten kinetics. allosteric site that site on an enzyme molecule which binds with a nonsubstrate molecule, inducing a conformational change that results in an alteration of the affinity of the enzyme for its substrate. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
|
| ? Mentioned in | ? References in periodicals archive | |
|---|---|---|
Channels return to the allosterically closed
configuration during membrane repolarization (Taylor 1994). The companies will apply Cue Biotech's Cue-Quest screening
technology to multiple GPCR targets in their efforts to identify and
develop novel small molecules that allosterically modulate important CNS
targets. 2+]
inhibits NMDAR function is by binding to a divalent cation site
associated with the glycine site and allosterically inhibiting glycine
binding (Hashemzadeh-Gargari and Guilarte 1999). |
| Medical Dictionary |
| Free Tools: |
For surfers:
Free toolbar & extensions |
Word of the Day |
Help
For webmasters: Free content | Linking | Lookup box | Double-click lookup | Partner with us |
|---|