allosteric site

site (sīt) a place, position, or locus.

allosteric site a site on a multi-subunit enzyme that is not the substrate binding site but that when reversibly bound by an effector induces a conformational change in the enzyme, altering its catalytic properties.

antigen-binding site , antigen-combining site the region of the antibody molecule that binds to antigens.

binding site in an enzyme or other protein, the three-dimensional configuration of specific groups on specific amino acids that binds specific compounds, such as substrates or effectors, with high affinity and specificity.

operator site a site adjacent to the structural genes in the operon, where repressor molecules are bound, thereby inhibiting the transcription of the genes in the adjacent operon.

restriction site a base sequence in a DNA segment recognized by a particular restriction endonuclease.

allosteric site

The place on an enzyme where a molecule that is not a substrate may bind, thus changing the shape of the enzyme and influencing its ability to be active.

allosteric [al″o-ster´ik]

pertaining to an effect produced on the biological function of a protein by a compound not directly involved in that function (an allosteric effector) or to regulation of an enzyme involving cooperativity between multiple binding sites (allosteric sites).

allosteric site that subunit of an enzyme molecule which binds with a nonsubstrate molecule, inducing a change in form or shape that results in inactivation of the enzyme for its substrate.

allosteric

pertaining to an effect on the biological function of a protein, produced by a compound not directly involved in that function (an allosteric effector) or to regulation of an enzyme involving cooperativity between multiple binding sites (allosteric sites).

allosteric enzymes

any enzymes containing an allosteric site, where effector molecules can bind to increase or decrease the rate of reaction, in addition to an active site for substrate binding. Allosteric enzymes exhibit sigmoidal rather than Michaelis-Menten kinetics.

allosteric site

that site on an enzyme molecule which binds with a nonsubstrate molecule, inducing a conformational change that results in an alteration of the affinity of the enzyme for its substrate.

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activating enzyme activation allosteric allosteric sites allostery binding site brancher enzyme debrancher enzyme debranching enzyme enzyme induced enzyme inducible enzyme lymphocyte activation repressible enzyme restriction site site	The Ii-Key motif from the Ii protein acts at an allosteric site adjacent to the MHC class II antigenic peptide-binding trough to enhance presentation of covalently linked epitopes 200-500 times in vitro. GENEREX PRESENTS POTENTIAL USES OF RAPIDMIST by Biotech Equipment Update Based on kinetic data, it has previously been reported that hEST may contain an allosteric site (Zhang et al. Crystallographic analysis of a hydroxylated polychlorinated biphenyl ... by Negishi, Masahiko / Environmental Health Perspectives In its lead inflammation program, Locus has created exquisitely selective p38 inhibitors which bind to p38 at an allosteric site and do not involve the ATP site. Locus Pharmaceuticals Completes $30.2 Million Financing Round by Business Wire	Allopathic allopathic physician allopathy allopentaploid allophenic alloplasia alloplast alloplastic alloplastic maneuver alloplasty alloploid alloploidy allopolyploid allopolyploidy allopsychic allopurinol allopurinol sodium alloreactive alloreactivity allorhythmia allosensitization Allosex Avoidance allosome allostatic load allosteric allosteric site allosteric sites allosterism allostery allotetraploid allotherm allotope allotransplant allotransplantation allotrichia circumscripta allotrio- allotriodontia allotriogeustia allotriophagia allotriploid allotrope allotrophic allotropic allotropism allotropy allotype allowable benefits allowable charge allowable costs allowable dose allowable error	Allosaurus fragilis allosauruses allosauruses allosensitization Alloseric enzyme Allosex Avoidance allosome allosome Allostasis Allostatic load Allostatic load allosteric allosteric allosteric allosteric activation allosteric activation allosteric activation Allosteric Control allosteric effector allosteric effector allosteric effector Allosteric enzyme Allosteric enzyme Allosteric enzyme allosteric enzymes allosteric enzymes allosteric modulator Allosteric regulation Allosteric regulation Allosteric regulation allosteric site allosteric sites allosteric transition allosterically allosterically allosterism allostery allostery allostery allot allot allot allot allot the parts allot to alloted Allotetraploid Allotetraploid Allotetraploid Allotetraploidy Allotetraploidy Allotetraploidy Allotheism Allotheria allotherm allothigene allothimorph allothogene allothogenic alloting allotment

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activating enzyme
activation
allosteric
allosteric sites
allostery
binding site
brancher enzyme
debrancher enzyme
debranching enzyme
enzyme
induced enzyme
inducible enzyme
lymphocyte activation
repressible enzyme
restriction site
site

The Ii-Key motif from the Ii protein acts at an allosteric site adjacent to the MHC class II antigenic peptide-binding trough to enhance presentation of covalently linked epitopes 200-500 times in vitro.

GENEREX PRESENTS POTENTIAL USES OF RAPIDMIST by Biotech Equipment Update

Based on kinetic data, it has previously been reported that hEST may contain an allosteric site (Zhang et al.

Crystallographic analysis of a hydroxylated polychlorinated biphenyl ... by Negishi, Masahiko / Environmental Health Perspectives

In its lead inflammation program, Locus has created exquisitely selective p38 inhibitors which bind to p38 at an allosteric site and do not involve the ATP site.

Locus Pharmaceuticals Completes $30.2 Million Financing Round by Business Wire