allostatic load


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allostatic load

a term coined as a more precise alternative to the term stress, used to refer to environmental challenges that cause an organism to begin efforts to maintain stability (allostasis).

al·lo·stat·ic load

(al'ō-stat'ik lōd)
The physiologic consequences of adapting to repeated or chronic stress: can accelerate disease processes.
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Indeed, newer variants of the allostatic load model incorporate primary (e.
Blending this theory with McEwen's stress theory of allostasis allows one to posit that exposure to early life stressors may increase the allostatic load for the person recovering from TBI, thereby increasing the likelihood of depression.
The related concept of allostatic load refers to the cumulative physiologic degradation, over the life course, that can result from chronic stress exposure, and the accompanying long-term shift that occurs in the body's homeostatic functions, with harmful consequences (Geronimus 1992; McEwen 1998; Seeman et al.
Two possible explanations of the relationship between pathology and social conditions lie in the disablement process model and the allostatic load model.
The first type of allostatic load is simply too much stress in the form of repeated events that cause repeated elevations of stress mediators over long periods of time with insufficient relief.
This allostatic load may lead to the manifestation of psychological, emotional, behavioral, immune, or metabolic disorders that is often associated with a flattening of the diurnal cortisol curve and a lack of postpubertal sex differences.
Sexual orientation and disclosure in relation to psychiatric symptoms, diurnal cortisol and allostatic load.
Similarly, the association between blood lead (BPb) and hypertension was stronger in adults with high, compared to low, allostatic load scores, which are a measure of the cumulative dysfunction of physiological systems due to psychosocial stress (McEwen 1998; Zota et al.
McEwen and Stellar (1993) embellished on the principle of allostasis by defining a new concept that these authors labeled allostatic load.
The wear and tear on the body, also referred to as the allostatic load, results from either too much stress or inefficient management of stress.