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alloreactive |
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alloreactive /al·lo·re·ac·tive/ (-re-ak´tiv) pertaining to the immune response in reaction to a transplanted allograft.
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No references found | Prevention of Acute Humoral Rejection with C5 Inhibition," * "Prevention of Endothelial Activation with C5 Inhibition in Positive-Crossmatch Kidney Transplants" * "Anti-C5 mAb Plus Low Dose CTLA4 Ig Inhibit Alloreactive T Cells and Prolong Heart Graft Survival in Mice," * "Complement C5 Inhibitor - Is It Useful in Antibody-Mediated Rejection? Subsequent experiments addressed whether PRN treatment of CTLs directly inhibits their activation and revealed that 1[degrees] alloreactive CTLs exposed to PRN are unimpaired in their proliferative response and only marginally inhibited in their lytic activity. Instead of getting a full complement of T cells from the donor, he said, patients will receive T cells that have been selectively depleted of the alloreactive T cells that researchers believe cause GVHD. |
alloreactive |
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