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alloimmunization

   Also found in: Wikipedia 0.02 sec.
alloimmunization /al·lo·im·mu·ni·za·tion/ (-im?u-ni-za´shun) an immune response generated in an individual or strain of one species by an alloantigen from a different individual or strain of the same species.
alloimmunization
development of antibodies in response to alloantigens; antigens derived from a genetically dissimilar animal of the same species. See also alloantigen.

alloimmunization of pregnancy
sensitization of the dam against fetal red blood cell antigens that leak into the maternal circulation across the placenta or during parturition is uncommon except in the mare and sow where it gives rise to alloimmune hemolytic anemia of the newborn.


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The decision is based on the evidence that leukocyte reduction reduces non-hemolytic febrile reactions, prevents alloimmunization, reduces transmission of cytomegalovirus (CMV), and may reduce transfusion-related suppression of the immune system.
Clinical studies have shown that filtering out white blood cells reduces a wide variety of adverse transfusion reactions including non-hemolytic febrile transfusion reactions, alloimmunization, transmission of pathogens such as cytomegalovirus (CMV), and suppression of the immune system.
The decision is based on the evidence that leukocyte reduction reduces non-hemolytic febrile reactions, prevents alloimmunization, reduces transmission of cytomegalovirus (CMV), and may reduce transfusion-related suppression of the immune system.
 
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