In the neonatal period, neutropenia suggests 4 common etiologies: (a) bacterial infection, (b) neonatal alloimmune
neutropenia (NAIN), (c) neutropenia related to maternal hypertension, or (d) congenital viral infections (3).
Additionally, factors other than chromosomal or genetic may be associated with EPL and were not tested in the present study, such as certain autoimmune factors including anti-phospholipid, anti-cardiolipin antibodies and lupus anticoagulant, alloimmune
factors, inherited thrombophilias, certain endocrine factors as associated with polycystic ovarian syndrome or luteal phase deficiency and certain environmental factors.
In light of new insights into the mechanisms of innate immunity on one hand and the essential role of regulatory T cells in controlling alloimmune
responses on the other hand, potential clinical tools to generate tolerogenic dendritic cells are explored.
All funds raised will go to the Nait charity which supports families and provides information about the rare genetic disorder neonatal alloimmune
Therefore, Evans syndrome (ES) should be presented separetly then autoimmune hemolytic anemia (AIHA) as of Wiskott-Aldrich syndrome (WAS) in which Coombs positivity may develop as of alloimmune
At four days old, Logan was diagnosed with neonatal alloimmune
thrombocytopenia, a rare condition that caused Kellie's antibodies to attack her baby's platelets.
Therefore, a "maternal microchimerism" hypothesis was proposed, whereby both immune cells and biliary epithelial cells of maternal origin are found in increased numbers in patients with biliary atresia, raising the possibility that an alloimmune
or a graft-versus-host-like phenomenon may be part of the pathogenesis of this disease (Figure 1).
Speaking about the winners of Medicine prize, Al-Othaimeen said Berkowitz and Bussel of the Columbia Medical Center in New York worked together for more than two decades to study the natural history, optimal diagnostic criteria and management of pregnant women having fetuses infected with alloimmune
thrombocytopenia is a rare disease causing serious thrombocytopenia during neotatal period.
Coverage encompasses cellular changes, feto-maternal alloimmune
syndromes, thromboembolism and anticoagulation, thromophilia and fetal loss, hemorrhagic disorders, microangiopathies, and malignant conditions.
response is the strongest immune response that occurs in humans, and is mediated by presentation of foreign antigens by human leukocyte antigens.
Systemic enzyme support is an effective immuno-modulator for both autoimmune and alloimmune