alloimmune


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al·lo·im·mune

(al'ō-im-yūn'),
Immune to an allogenic antigen.
[allo- + immune]

alloimmune

/al·lo·im·mune/ (al″o-ĭ-mūn´) specifically immune to an allogeneic antigen.

alloimmune

adjective Relating to alloimmunization or a nonself immune reaction

al·lo·im·mune

(al'ō-im-yūn')
Immune to an allogenic antigen.
[allo- + immune]

alloimmune

immunity to an alloantigen.

alloimmune hemolytic anemia of the newborn
occurs in humans, where it is also called Rh disease, in foals as a naturally occurring disease, and in pigs and cattle receiving vaccines containing allotypic red blood cell antigens. In naturally occurring Rh-like syndrome, there are usually no untoward consequences for the first pregnancy, but at parturition red blood cells from the offspring enter the maternal circulation and, if the red blood cell antigens differ from the dam, result in the production of antibodies. A subsequent pregnancy from the same mating in which an offspring of the same blood type is produced will result in a hemolytic anemia in the offspring when maternal antibodies are acquired in the colostrum.
Enlarge picture
Hemolytic anemia of the newborn. By permission from Tizard IR, Veterinary Immunology An Introduction, Saunders, 2001
References in periodicals archive ?
In the neonatal period, neutropenia suggests 4 common etiologies: (a) bacterial infection, (b) neonatal alloimmune neutropenia (NAIN), (c) neutropenia related to maternal hypertension, or (d) congenital viral infections (3).
Additionally, factors other than chromosomal or genetic may be associated with EPL and were not tested in the present study, such as certain autoimmune factors including anti-phospholipid, anti-cardiolipin antibodies and lupus anticoagulant, alloimmune factors, inherited thrombophilias, certain endocrine factors as associated with polycystic ovarian syndrome or luteal phase deficiency and certain environmental factors.
In light of new insights into the mechanisms of innate immunity on one hand and the essential role of regulatory T cells in controlling alloimmune responses on the other hand, potential clinical tools to generate tolerogenic dendritic cells are explored.
All funds raised will go to the Nait charity which supports families and provides information about the rare genetic disorder neonatal alloimmune thrombocytopenia.
Therefore, Evans syndrome (ES) should be presented separetly then autoimmune hemolytic anemia (AIHA) as of Wiskott-Aldrich syndrome (WAS) in which Coombs positivity may develop as of alloimmune reaction.
At four days old, Logan was diagnosed with neonatal alloimmune thrombocytopenia, a rare condition that caused Kellie's antibodies to attack her baby's platelets.
Therefore, a "maternal microchimerism" hypothesis was proposed, whereby both immune cells and biliary epithelial cells of maternal origin are found in increased numbers in patients with biliary atresia, raising the possibility that an alloimmune or a graft-versus-host-like phenomenon may be part of the pathogenesis of this disease (Figure 1).
Speaking about the winners of Medicine prize, Al-Othaimeen said Berkowitz and Bussel of the Columbia Medical Center in New York worked together for more than two decades to study the natural history, optimal diagnostic criteria and management of pregnant women having fetuses infected with alloimmune thrombocytopenia.
Neonatal alloimmune thrombocytopenia is a rare disease causing serious thrombocytopenia during neotatal period.
Coverage encompasses cellular changes, feto-maternal alloimmune syndromes, thromboembolism and anticoagulation, thromophilia and fetal loss, hemorrhagic disorders, microangiopathies, and malignant conditions.
The alloimmune response is the strongest immune response that occurs in humans, and is mediated by presentation of foreign antigens by human leukocyte antigens.
Systemic enzyme support is an effective immuno-modulator for both autoimmune and alloimmune infertility.