allogeneic transplant

allogeneic transplant

Immunology The transplantation of an organ or tissue from a genetically matched relative or other donor
References in periodicals archive ?
Abstract #2473: Use of High-Throughput Sequencing (HTS) of TCRE to Determine the Kinetics of Graft-Versus-Lymphoma (GVL) Effect and T-Cell Repertoire Profiles after Allogeneic Transplant Presenter: Wen-Kai Weng Session: 721.
The CliniMACS CD34 Reagent System decreases the risk of developing GVHD, a life-threatening complication that can occur following an allogeneic transplant, in which T cells from the donor attack various tissues of the recipient.
She received alemtuzumab with her first allogeneic transplant and conditioning with antithymocyte globulin before her second transplant, resulting in significant in vivo T-cell depletion; she was also receiving adrenal corticosteroids.
Allogeneic transplant is performed only in major urban tertiary referral centres.
As close a match as possible is desired for an allogeneic transplant to be successful.
Rowe of the Ramdam Medical Center in Haifa, Israel, said that earlier data support the use of allogeneic transplant in Philadelphia chromosome-positive (Ph+) and other high-risk patients, although its efficacy in other patients has not yet been established.
The use of allogeneic transplant has not been widespread, however, because of the risk of graft-versus-host disease (GVHD), a potentially fatal complication caused by contaminating T cells.
Added to autologous transplantation with the patient's own marrow, there is allogeneic transplant using someone else's marrow, and now miniallogeneic.
Impact of allogeneic transplant on clonal heterogeneity in MDS
This facility will give hope to many cancer patients in and around Bangalore as there are very few hospitals in South India providing allogeneic transplant, which involves using stem cells from a donor with a similar genetic makeup.
Approximately 70 percent of patients who need an allogeneic transplant do not have a matching donor in their family and depend on an unrelated donor.
An allogeneic transplant uses blood-forming cells from a volunteer or from cord blood unit.