allergic mucin

allergic mucin

A term of art for a histopathological finding in allergic fungal sinusitis in which mucin has a characteristic “tiger striping” due to layering of eosinophils, mucin and cellular debris.
References in periodicals archive ?
Histologic examination of the diseased tissue identified allergic mucin with 70% eosinophils and no fungal hyphae.
Sinusitis is characterized by the presence of allergic mucin and elevated IgE; treatment includes surgery plus corticosteroids.
b and c (from Allergic Mucin With and Without Fungus: A Comparative Clinicopathologic Analysis--Lara & Gomez) 4.
This inspissated allergic mucin (classically described as "peanut butter" mucus) may take the form of rubbery plugs that can be expelled from the nose.
The allergic mucin mass may expand to completely fill the sinus and enter the orbit or skull base.
Identification of allergic mucin on histopathologic evaluation of material from the sinus.
Characteristic allergic mucin is seen in histologic specimens and serves as an indication to the surgeon and pathologist to be aware of and look for fungal organisms.
Allergic fungal sinusitis, also known as allergic mucin and eosinophilic fungal rhinosinusitis, is an allergic response in the sinonasal tract mucosa to aerosolized fungal allergens, amplified and perpetuated by eosinophils.
The diagnostic criteria of AFS include (1) chronic rhinosinusitis (confirmed by computed tomographic scan); (2) the presence of allergic mucin (predominantly eosinophils and their degenerated by-products); and (3) the presence of fungal organisms within that mucin confirmed by histology or culture.
The patient did have allergic fungal sinusitis and presented as you described, with typical allergic mucin.
5) They described this a s allergic mucin, which consisted of degenerating eosinophils, desquamated respiratory epithelial cells, and Charcot-Leyden crystals.
Histologic examination of the maxillary and sphenoid contents did not detect any allergic mucin or fungal elements.