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allergic granulomatosis

   Also found in: Encyclopedia 0.01 sec.
allergic granulomatosis.
granulomatosis [gran″u-lo″mah-to´sis]
any condition involving the formation of multiple granulomas.
allergic granulomatosis churg-strauss syndrome.
eosinophilic granulomatosis Langerhans cell histiocytosis.
Langerhans cell granulomatosis Langerhans cell histiocytosis.
lymphomatoid granulomatosis a multisystem disease involving predominantly the lungs, skin, central nervous system, and kidneys, caused by invasion and destruction of vessels by atypical lymphoreticular cells. Many affected patients develop frank lymphoma. It usually affects males, and the most frequent presenting symptoms are cough, shortness of breath, and chest pain. Extrapulmonary manifestations are common, with skin lesions being present in many cases.
granulomatosis sidero´tica a condition in which brownish nodules are seen in the enlarged spleen.
Wegener's granulomatosis a multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic, small vessel vasculitis, which is generally considered to represent an aberrant hypersensitivity reaction to an unknown antigen.


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Churg Strauss syndrome, also known as allergic granulomatosis, is an autoimmune disorder characterised by accumulated antibodies, inflammation of blood vessels, and abnormal clustering of white blood cells.
Churg-Strauss syndrome (CSS) was also labeled allergic granulomatosis and angiitis because of the presence, predominantly in extranodal locations, of granulomatous inflammation along with eosinophilic vasculitis.
 
 
 
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