allele frequency

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allele frequency

A term used in population genetics for the number of copies of a particular allele divided by the number of copies of all alleles at that specific genetic locus in a population of interest. Allele frequency is a measure of a population’s genetic diversity: the higher the allele frequency, the greater the population’s consanguinity.
Allele frequencyclick for a larger image
Fig. 23 Allele frequency . Calculation of allele frequency from genotype frequency.

allele frequency

or

gene frequency

the proportion of a particular ALLELE of a gene in a population, relative to other alleles of the same gene. For example, if a gene has two alleles, A and a , and the frequency of A is 0.6, then the frequency of a will be 1.0 - 0.6 = 0.4. The allele frequency can be calculated from the GENOTYPE FREQUENCY; See Fig. 23 .
References in periodicals archive ?
It is important to highlight that the allelic frequency for the Phe508del was of 25% in the studied population, which differs from much higher figures observed in studies with Caucasian populations.
In our study, allelic frequency for casein gene was 50% for C allele and 50% for T allele.
95 TABLE II ALLELIC FREQUENCY OF FOUND MUTATIONS FOR THE SIX EXONS STUDIED (Data of exons 10, 11, 19,20 and 21) Mutation This study Perez et al.
Odds ratio (OR) was calculated using the formula: OR = ad/bc; where a--analyzed allelic frequency in patients; b--analyzed allelic frequency in the control sample; c and d--total frequency of other alleles in patients and controls, respectively.
In addition to high TNF-[alpha] concentration, this study showed a cross-sectional association between allelic frequency and markers of HIV disease progression, which was indicated by high bystander [T.
There may be important differences in the allelic frequency of these mutations in different European populations, and they may exhibit regional variations in Europe (7-10).
In this method no significant differences observed in allelic frequency and observed heterozygosity between breeders and their progenies, to keep the level of heterozigocity may is due to the method of crossing.
The present study aims to determine the allelic frequency of SNPs across intracellular folate metabolic pathway in healthy Indian subjects.
The maximum likelihood estimate for the inferred null allelic frequency was calculated for each locus using ML-NullFreq (Kalinowski & Taper 2006).
This increase of allelic frequency is better reflected in changes in antigenic profiles.
An FVL allelic frequency of about 2% was initially reported in the Dutch population.