alfentanil


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alfentanil

 [al-fen´tah-nil]
an opioid analgesic of rapid onset and short duration derived from fentanyl; the hydrochloride salt is used as a primary agent for induction of general anesthesia, as an adjunct in maintenance of general anesthesia, and as an adjunct to regional or local anesthesia.

alfentanil

/al·fen·ta·nil/ (al-fen´tah-nil) an opioid analgesic of rapid onset and short duration derived from fentanyl, used as the hydrochloride salt in the induction of general anesthesia and as an adjunct in general, regional, and local anesthesia.

alfentanil

A potent, short-acting opioid analgaesic and fentanyl analogue which is 10-fold stronger than morphine. It is an OP3 mu agonist.
 
Mechanism of action
Modulation of the sympathetic response to endotracheal intubation and surgical stimulation.
 
Cons
Profound respiratory depression and skeletal muscle rigidity.

alfentanil

Anesthesiology An opioid analgesic that is 10-fold more potent than morphine Cons Profound respiratory depression and skeletal muscle rigidity. See Opioid anesthetic. Cf Muscle relaxant.

alfentanil

A narcotic analgesic drug used before and during anaesthesia. A brand name is Rapifen.

alfentanil

A narcotic-type pain-killing drug. A brand name is Rapifen.

alfentanil

an opioid analgesic; a derivative of fentanyl with lower potency but more rapid action.
References in periodicals archive ?
Medical records reportedly show he was given Alfentanil, an opiate 30 times the strength of oral morphine, and Midazolam, a strong sedative.
1 N01AH02 alfentanil solution for injection or infusion 1mg / 2ml, 0.
Comparative spinal distribution and clearance kinetics of intrathecally administered morphine, fentanyl, alfentanil and sufentanil.
This effect was reported to be dose related such that progressively increasing doses of alfentanil decreased HR in a dose dependent manner in dogs (ARNDT et al.
Many cases have been observed in which opioid-associated dystonia and rigidity were observed following use of alfentanil and fentanyl in Parkinson's patients (8,9).
used additional alfentanil bolus before ETS due to rapid onset of alfentanil for analgesia.
All three drugs showed similar hemodynamic and ventilatory responses but fentanyl bolus resulted in greater hemodynamic instability than remifentanil or alfentanil infusion.
8% sevoflurane inhalation and alfentanil in hypertensive patients.
These methods include deepening of the plane of anesthesia, [4,7] topical anesthesia of laryngopharynx and epiglottis, [8-10] and use of fentanyl and alfentanil before intubation, which produce significant attenuation of cardiovascular response during intubation.
5 [micro]g/kg), or with alfentanil (15 [micro]g/kg) they were ventilated with 100% oxygen.
Alfentanil was tested against lignocaine, and combination of both was tested as well.
Effects of fentanyl, alfentanil, remifentanil and sufentanil on loss of consciousness and bispectral index during propofol induction of anaesthesia.