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alendronate

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alendronate /alen·dro·nate/ (ah-len´dro-nāt) a bisphosphonate calcium-regulating agent used in the form of the sodium salt to inhibit the resorption of bone in the treatment of osteitis deformans, osteoporosis, and hypercalcemia related to malignancy.
Alendronate
A nonhormonal drug used to treat osteoporosis in postmenopausal women.
Mentioned in: Osteoporosis
alendronate,
a bone-resorption inhibitor.
indications This drug is used to treat osteoporosis in postmenopausal women and Paget's disease.
contraindication Known hypersensitivity to biphosphonates prohibits the use of this drug.
adverse effects Side effects include anemia, hypokalemia, hypomagnesemia, hypophosphatemia, osteonecrosis of the jaw, abdominal pain, anorexia, constipation, nausea, vomiting, bone pain, hypertension, urinary tract infection, and fluid overload.
alendronate [ah-len´dro-nāt]
a calcium-regulating agent used in the form of the sodium salt to inhibit resorption of bone in the treatment of osteitis deformans, osteoporosis, and hypercalcemia related to malignancy; administered orally.
alendronate
Fosamax® Endocrinology A biphosphonate used to treat postmenopausal osteoporosis and Paget's disease of bone. See Osteoporosis. Cf Salmon calcitonin.
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They experience intolerable side effects from the standard drug prescribed for the condition, alendronate, which costs less than pounds 50 a year.
Brittle bone patients denied drugs by Daily Post (Liverpool, England)
Researchers in Australia and the US found that almost all of those treated with alendronate showed at least a "modest" increase in their bone mineral density - and this effect did not vary much between individuals.
Bone test fears by Evening Chronicle (Newcastle, England)
But when alendronate (Fosamax), the first bisphosphonate, and others got approved, we cautioned that the drugs' longterm effects also needed to be carefully evaluated.
Osteo express: bisphosphonate safety by Women's Health Activist
 
 
 
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