alcohol septal ablation


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alcohol septal ablation

A treatment for hypertrophic obstructive cardiomyopathy in which coronary artery catheterization is used to isolate the septal artery that supplies blood to the hypertrophied myocardium. Pure alcohol is injected into the artery, causing it to obstruct. The thickened heart muscle nourished by the septal artery is deprived of oxygen and dies. The procedure is a controlled and monitored myocardial infarction (heart attack), designed to eliminate the overdeveloped muscle blocking blood flow out of the heart. It is used in carefully selected patients as an alternative to surgical removal of the obstructing muscle (surgical myectomy).
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Also in a related study, a treatment called alcohol septal ablation is being revealed as an effective treatment for severe cases of HCM.
In addition, the research provides a suggestion why a frequently used therapy, alcohol septal ablation, is an effective treatment for symptomatic patients who remain symptomatic despite optimal medical treatment," he added.
For patients > 40 years old, and also not suitable for surgery because of comorbidities, alcohol septal ablation is viable alternative therapy for relief of obstruction and improvement of symptoms.
Key words: Hypertrophic cardiomyopathy, obstructive HCM treatment, disopyramide, septal myectomy, alcohol septal ablation, echocardiography
Obstructed patients who fail medical therapy, defined as lack of gradient reduction below 50 mmHg and persistent disabling symptoms, are usually offered invasive treatment: surgical septal myectomy, alcohol septal ablation, or DDD pacemaker.
The short-term success of alcohol septal ablation approaches 90% (2), but long-term risks and follow-up data are not yet available.
This brief review summarizes how patients are selected for myectomy or alcohol septal ablation and reviews results for both procedures.
Key words: Hypertrophic cardiomyopathy, myectomy, alcohol septal ablation
Cardiovascular/Peripheral Vascular Surgery: Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy; Aortic Aneurysm Repair - Criteria and Options; Aortic and/or valve replacement; Atherectomy, peripheral; Atrial septal defect, repair; Carotid body tumor resection (Glomectomy); Carotid endarterectomy - Indications, LOS; Carotid/Vertebral Artery Angioplasty and Stenting Procedures; Coronary artery bypass graft(s) surgery (CABG) - Indications, LOS; Extracranial-Intracranial arterial bypass surgery; Heart volume reduction surgery;
Percutaneous alcohol septal ablation has also been utilized, although its ultimate utility and safety remain controversial (5).

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