alatrofloxacin


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alatrofloxacin

 [ah-lat″ro-flok´sah-sin]
a broad-spectrum antibacterial that is the prodrug of trovafloxicin, to which it is rapidly converted after intravenous infusion; used in the form of the mesylate salt.

alatrofloxacin

/alat·ro·flox·a·cin/ (ah-lat″ro-flok´sah-sin) a broad-spectrum antibacterial that is the prodrug of trovafloxicin, to which it is rapidly converted after intravenous infusion; used as the mesylate salt.

alatrofloxacin

[ah-lat′ro-flok′sah-sin]
a broad-spectrum antibacterial that is the prodrug of trovafloxacin, to which it is rapidly converted after IV infusion; it is used in the form of the mesylate salt.

alatrofloxacin/trovafloxacin

a quinolone antibiotic.
indications This drug is used to treat nosocomial pneumonia, community-acquired pneumonia, chronic bronchitis, acute sinusitis, complicated intraabdominal infections, infections of the skin and skin structure, urinary tract infections, chronic bacterial prostatitis, urethral gonorrhea in males, pelvic inflammatory disease, and cervicitis caused by susceptible organisms.
contraindications Known hypersensitivity to quinolones, seizure disorders, cerebral atherosclerosis, and photosensitivity prohibit the use of this drug.
adverse effects Life-threatening side effects include pseudomembranous colitis and thrombocytopenia. Other adverse effects include headache, dizziness, insomnia, anxiety, nausea, flatulence, vomiting, diarrhea, abdominal pain, vaginitis, crystalluria, rash, pruritus, and photosensitivity.
References in periodicals archive ?
anthracis Sterne) to 21 sequential subcultures in subinhibitory concentrations of doxycycline, ciprofloxacin, alatrofloxacin, and gatifloxacin.
anthracis longer than were ciprofloxacin or alatrofloxacin, while clarithromycin was effective longer than either erythromycin or azithromycin.
In December 1996, Pfizer submitted a New Drug Application for Trovan, including both trovafloxacin, an oral broad-spectrum quinolone antibiotic, and its intravenous form alatrofloxacin.