alanine transferase


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alanine transferase

an intracellular enzyme in amino acid and carbohydrate metabolism found in high concentration in brain, liver, and muscle. An increased level indicates necrosis or disease in these tissues. See also alanine aminotransferase.
References in periodicals archive ?
Alanine transferase, aspartate trasnferrase, alkaline phosphatase and gamma-glutamyl transpeptidase levels were 946, 1047, 396 and 203 U/L, respectively.
Patients in the teriflunomide group experienced more nausea, diarrhea, increases in alanine transferase, and hair thinning than did those in the placebo group, but these effects were mild.
Adverse events occurring at a higher rate in the teriflunomide groups were diarrhea, nausea, alanine transferase increases that were mainly mild and asymptomatic with no dose effect and mild hair thinning and hair loss which rarely led to treatment discontinuation.
98 mg/ dL), and abnormal liver function (aspartate aminotransferase 49 U/L and alanine transferase 60 U/L).
The most common grade 3-4 biochemical abnormalities were alanine transferase elevation (13%), bilirubin (25%), hypophosphatemia (32%), lipase elevation (44%), and hyperglycemia (33%), Dr.
As a result, in mice administered the anti-CXCL10 neutralizing antibody the serum alanine transferase (ALT3) level was significantly lower, and histologically too the area of necrotized hepatic cells was strikingly reduced.
Serum alanine transferase (ALT) level was 750 U/L, serum aspartate transferase (AST) 445 U/L, serum alkaline phosphatase (ALP) 395 U/L, serum [gamma]-glutamyl transpeptidase (GGT) 289 U/L and total bilirubin concentration was 3.
Sixty-nine percent (38/55) of patients who received Hepsera for 240 weeks exhibited improvement in liver function, as measured by normalization of serum alanine transferase (ALT) levels.
The most frequently reported BZL101-related adverse events were: diarrhea (40%), nausea (30%), headache (20%), and increased amino alanine transferase (20%).
6 Alkaline phosphatase (IU/L) 240 83 125-476 Aspartate transferase (IU/L) 46 26 20-128 Alanine transferase (IU/L) (c) 81 51 10-210 Sodium (mg/dL) 146 4 141-152 Chloride (mg/dL) 104 4 97-111 Platelets (x[10.
Serum alanine transferase levels declined in patients receiving rosglitazone, perhaps because the drug decreased liver fat content.
The most common nonhematologic side effect was elevated AST/ALT (aspartate amino transferase/ amino alanine transferase - enzymes monitored to assess liver function) occurring in 21 percent of patients.