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afterload |
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afterload /af·ter·load/ (-lōd″) the force against which cardiac muscle shortens: in isolated muscle, the force resisting shortening after the muscle is stimulated to contract; in the intact heart, the pressure against which the ventricle ejects blood.
afterload Etymology: AS, aefter + ME lod the load, or resistance, against which the left ventricle must eject its volume of blood during contraction. The resistance is produced by the volume of blood already in the vascular system and by the constriction of the vessel walls. afterload [af´ter-lōd] the tension developed by the heart during contraction; it is an important determinant of myocardial energy consumption, as it represents the resistance against which the ventricle must pump and indicates how much effort the ventricles must put forth to force blood into the systemic circulation. Factors that increase afterload include aortic and pulmonarystenosis, systemic and pulmonary hypertension, and high peripheral resistance.
afterload see cardiac afterload.
afterload Cardiology The amount of hemodynamic pressure–peripheral vascular resistance downstream from the heart–which ↑ in heart failure 2º to aortic stenosis and HTN. Cf Preload Physiology The tension produced by heart
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