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afterload

   Also found in: Wikipedia 0.01 sec.
afterload /af·ter·load/ (-lōd″) the force against which cardiac muscle shortens: in isolated muscle, the force resisting shortening after the muscle is stimulated to contract; in the intact heart, the pressure against which the ventricle ejects blood.
af·ter·load (ftr-ld)
n.
1. The arrangement of a muscle so that it lifts a weight from an adjustable support or works against a constant opposing force to which it is not exposed when at rest.
2. The load or force thus encountered.

afterload
Etymology: AS, aefter + ME lod
the load, or resistance, against which the left ventricle must eject its volume of blood during contraction. The resistance is produced by the volume of blood already in the vascular system and by the constriction of the vessel walls.

afterload [af´ter-lōd]
the tension developed by the heart during contraction; it is an important determinant of myocardial energy consumption, as it represents the resistance against which the ventricle must pump and indicates how much effort the ventricles must put forth to force blood into the systemic circulation. Factors that increase afterload include aortic and pulmonarystenosis, systemic and pulmonary hypertension, and high peripheral resistance.

afterload
see cardiac afterload.

afterload
Cardiology The amount of hemodynamic pressure–peripheral vascular resistance downstream from the heart–which ↑ in heart failure 2º to aortic stenosis and HTN. Cf Preload Physiology The tension produced by heart muscle after contraction.


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Current first-line treatments target the removal of excess fluid (diuresis) and preload and afterload reduction (vasodilation).
These studies included: Survival and Ventricular Enlargement (SAVE), 1987-1992; Clinical Evaluation of the Medtronic 4068 Lead System, 1992-1993; Cholesterol and Recurrent Events (CARE), 1990 to 1993; Healing and Early Afterload Reducing Therapy (HEART), 1993-1995.
Second, the possibility of impeding venous return and augmenting right ventricular afterload by high airway pressure needed to be confronted.
 
 
 
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