afterload


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afterload

 [af´ter-lōd]
the tension developed by the heart during contraction; it is an important determinant of myocardial energy consumption, as it represents the resistance against which the ventricle must pump and indicates how much effort the ventricles must put forth to force blood into the systemic circulation. Factors that increase afterload include aortic and pulmonarystenosis, systemic and pulmonary hypertension, and high peripheral resistance.

af·ter·load

(af'ter-lōd),
1. The arrangement of a muscle so that, in shortening, it lifts a weight from an adjustable support or otherwise does work against a constant opposing force to which it is not exposed at rest.
2. The load or force thus encountered in shortening.

afterload

/af·ter·load/ (-lōd″) the force against which cardiac muscle shortens: in isolated muscle, the force resisting shortening after the muscle is stimulated to contract; in the intact heart, the pressure against which the ventricle ejects blood.

afterload

Etymology: AS, aefter + ME lod
the load, or resistance, against which the left ventricle must eject its volume of blood during contraction. The resistance is produced by the volume of blood already in the vascular system and by the constriction of the vessel walls.

Afterload

Cardiology The amount of haemodynamic pressure (peripheral vascular resistance) downstream from the heart, which increased in heart failure secondary to aortic stenosis and hypertension. Cf Preload.
Physiology The tension produced by heart muscle after contraction.

afterload

Cardiology The amount of hemodynamic pressure–peripheral vascular resistance downstream from the heart–which ↑ in heart failure 2º to aortic stenosis and HTN. Cf Preload Physiology The tension produced by heart muscle after contraction.

af·ter·load

, after-load (af'tĕr-lōd)
1. The arrangement of a muscle so that, in shortening, it creates a force from an adjustable support or otherwise work against an opposing force to which it is not exposed at rest.
2. The load or force thus encountered in shortening.
3. That resistance against which the left ventricle must eject its volume of blood during contraction.

afterload

see cardiac afterload.
References in periodicals archive ?
2010), since the systolic function is dependent on factors such as preload, afterload, contractility, distensibility, coordinated contraction and heart rate (BOON, 2011).
4] Increased weight gain which is associated with increased lean and fat mass, along with the associated increase in total blood volume may be accompanied by an increase in stroke volume, cardiac output and circulatory preload and afterload that can lead to left ventricular hypertrophy and sustained rise in blood pressure.
In AWMI the RV dysfunction is predominantly due to LV dysfunction which causes acute increase in afterload of RV leading to contractile dysfunction of RV.
On the other hand, hypoxic vasoconstriction induces pulmonary hypertension and increases RV afterload.
In the early pregnancy an overall decrease in vascular tone leads to systemic vasodilatation and rise in arterial compliance, there is a possible role of release of vasopressin, [14] which causes hemodilution and with a reduction in viscosity, which potentiates fall in vascular resistance and contributing to fall in afterload.
The goal of our anesthetic management was to provide adequate maternal analgesia, prevent tachycardia, minimize maternal endogenous catecholamine release and maintain normal sinus rhythm while avoiding a rapid decrease in afterload or acute increase in preload.
Relaxation of bronchial and peripheral vascular smooth muscle reduces afterload in the heart (Kee et al.
The perfusion pressure was set at 15cm H2O for the preload and 80cm H2O for afterload to ensure an adequate coronary flow [26].
2] When the afterload is increased, for example by strong hand grip or squatting, the murmur is accentuated.
Additionally, OTC medications like pseudoephedrine, which many cough and cold products contain, can increase blood pressure and afterload," he noted.