adynamia episodica hereditaria

a·dy·nam·i·a ep·i·so·di·ca he·re·di·ta·ri·a

hyperkalemic periodic paralysis, without myotonia. See entries under paralysis.

adynamia episodica hereditaria

a condition of infancy, characterized by periodic muscle weakness and episodes of flaccid paralysis. It is inherited as an autosomal-dominant trait. Also called hyperkalemic periodic paralysis.

adynamia episodica hereditaria

An obsolete term defined as an autosomal dominant condition of early (infancy) onset characterised by episodic weakness, beginning in the lower extremities and spreading centrally, which is associated with hyperkalaemia. The episodes last up to an hour and typically follow a period of post-exercise rest.

Attributed to a defect in skeletal muscle sodium channels, it is an antiquated term for normokalaemic periodic paralysis, hyperkalemic periodic paralysis or periodic paralysis type II MIM 170500; adynamia episodica hereditaria is therefore best regarded as as inappropriate for working medical parlance.