adverse drug reactions


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adverse drug reactions

; ADRs un-intended and harmful effect of drug therapy, neither intended nor expected in normal therapeutic use (Table 1)
Table 1: Types of adverse drug reaction
TypeFeatures
ACommon, dose-related, predictable, augmented drug effect in patients showing excessive response to normal drug dosage; managed by dose reduction
BBizarre, rare, unpredictable, non-dose-related, immunological-based, severe drug reaction; drug must be withdrawn immediately
CGradual reduction of drug effectiveness over time; due to adaptation/habituation
DDelayed effects of drug
EEnd-of-use withdrawal reaction
FUnexpected failure of therapeutic effect, possibly due to interaction with another drug
References in periodicals archive ?
Additional Important Adverse Drug Reactions : The following occurred more frequently in LONSURF-treated patients compared to placebo: infections (27% vs 15%), and pulmonary emboli (2% vs 0%).
The Chinese regulations for disclosure and feedback of information about adverse drug reactions and events.
A method for estimating the probability of adverse drug reactions.
8) Although much has been published about these reactions in the long-term and acute care settings, little has been known until recently about the types of adverse drug reactions common in the outpatient setting, such as the dental office.
They claim adverse drug reactions have reached "epidemic proportions", with around 197,000 EU citizens dying every year because of the problem.
Adverse drug reactions in a department of systemic diseases-oriented internal medicine: prevalence, incidence, direct costs and avoidability.
Skin adverse drug reactions can be caused by a wide variety of agents.
CQC chief executive, Cynthia Bower, said: "Incidents related to medication can cause significant problems and not all adverse drug reactions are preventable, but it is important basic systems are working to minimise these risks.
Other new tests available include the ProGenotyper Filaggrin Mutation Detection Test, the latest in the company's menu of molecular assays to investigate skin diseases, and the T-Cell Rx assay, which adds to its line of tests for adverse drug reactions and assists physicians assessing patients who have experienced a delayed drug reaction.
Today's news comes after the medicines watchdog said last month that it had received 720 reports of adverse drug reactions (totalling 2,123 individual reactions) in the UK since the drug launched in 2006.
Abu Dhabi: The Ministry of Health and other health authorities are in the process of establishing a national pharmaco-vigilance programme to deal with adverse drug reactions and medication errors.
The figures for Adverse Drug Reactions (ADRs) describe patients who have an adverse reaction to prescriptions, over-the-counter medicines and those on sale in shops across the entire UK.

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