rickets /rick·ets/ (rik´ets) a condition due to vitamin D deficiency, especially in infancy and childhood, with disturbance of normal ossification, marked by bending and distortion of the bones, nodular enlargements on the ends and sides of the bones, delayed closure of the fontanelles, muscle pain, and sweating of the head.
adult rickets.
rickets (rik´
ts),
adult rickets osteomalacia.
familial hypophosphatemic rickets any of several inherited disorders of proximal renal tubule function causing phosphate loss, hypophosphatemia, and skeletal deformities, including rickets and osteomalacia.
fetal rickets achondroplasia.
hereditary hypophosphatemic rickets with hypercalciuria a form of familial hypophosphatemic rickets; hypophosphatemia is accompanied by elevated serum 1,25-dihydroxyvitamin D, increased intestinal absorption of calcium and phosphate, and hypercalciuria.
hypophosphatemic rickets any of a group of disorders characterized by rickets associated with hypophosphatemia, resulting from dietary phosphorus deficiency or due to defects in renal tubular function; skeletal deformities are present but hypocalcemia, myopathy, and tetany are absent and serum parathyroid hormone is normal.
oncogenous rickets oncogenous osteomalacia occurring in children.
pseudovitamin D–deficiency rickets vitamin D, sometimes specifically the type I form.
refractory rickets vitamin D
vitamin D–dependent rickets either of two (types I and II) inherited disorders characterized by myopathy, hypocalcemia, moderate hypophosphatemia, secondary hyperparathyroidism, and subnormal serum concentrations of 1,25-dihydroxyvitamin D; type I can be overcome by high doses of vitamin D, but type II cannot.
vitamin D–resistant rickets
2. any of a group of disorders characterized by rickets but not responding to high doses of vitamin D; most are forms of familial hypophosphatemic rickets.
| adult rickets n. See osteomalacia. |
adult rickets.
See osteomalacia.
rickets (rik´
ts),n a condition caused by deficiency of vitamin D or calcium in infants and children, with disturbance in the mineralization of osseous and dental tissues. Marked by bending and bowing of bones, nodular enlargements at the ends of bones, myalgia, delay in closure of fontanels, and other problems. See also osteomalacia.
rickets, adult,
n See osteomalacia.
rickets, refractory,
n See rickets, resistant.
rickets, renal,
n a disturbance marked by excessive excretion of phosphorus and calcium resulting from a lowered renal threshold of excretion of these mineral elements. See also osteodystrophy, renal.
rickets, resistant,
n (late rickets, refractory rickets), rickets that responds only to extremely large amounts of vitamin D.
Rickettsia
n a genus of microorganisms that combine aspects of both bacteria and viruses. Examples of rickettsial diseases are Rocky Mountain spotted fever and typhus.
rickets
a disease of young growing animals caused by a nutritional deficiency of phosphorus or vitamin D. There is a failure of calcification of osteoid and cartilage of the bones which become bowed and a persistence with enlargement of the epiphyses so that the joints appear swollen. The animals are lame and dentition is delayed. Radiological examination shows a wider and thicker growth plate.
adult rickets
osteomalacia; a rickets-like disease affecting adults.
fetal rickets
see achondroplasia.
hypervitaminosis D rickets
deposition of large amounts of osteoid matrix in the metaphyses with a delay in its mineralization occurs in feeding excessive amounts of vitamin D.
inherited rickets
affected piglets are normal at birth but develop rickets indistinguishable from classical rickets. There is a defect in calcium absorption.
renal rickets
see renal secondary hyperparathyroidism.
vitamin D-resistant rickets
a condition almost indistinguishable from ordinary rickets clinically but resistant to unusually large doses of vitamin D; it is often familial but may occur sporadically. In hypophosphatemic vitamin D-resistant rickets, hypophosphatemia is the main characteristic, while in hypocalcemic vitamin D-resistant rickets, the serum concentration of phosphate is within normal limits or nearly so, and the concentration of calcium is abnormally low.
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