adult rickets


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os·te·o·ma·la·ci·a

(os'tē-ō-mă-lā'shē-ă),
A disease in adults characterized by a gradual softening and bending of the bones with varying severity of pain; softening occurs because the bones contain osteoid tissue that has failed to calcify because of lack of vitamin D or renal tubular dysfunction; more common in women than in men, osteomalacia often begins during pregnancy.
[osteo- + G. malakia, softness]

adult rickets

adult osteomalacia

A generic term for bone disease characterised by poor mineralisation, which overlaps with osteoporosis, but differs therefrom in that there is calcium deficiency due to low dietary calcium or lack of vitamin D, and phosphate deficiency due to renal loss.

Aetiology
Low intake of calcium and vitamin D or phosphorus, renal tubular acidosis, chronic renal failure, malnutrition, malabsorption, hypophosphataemia, anti-convulsant therapy, coeliac disease, cancer-related osteolysis.
 
Clinical findings
Begins with vague symmetrical pain, increased bone sensitivity, proximal muscle weakness, difficulty in climbing stairs.

Imaging
Pseudofractures.
 
Management
Pharmacologic doses of vitamin D.

os·te·o·ma·la·ci·a

(os'tē-ō-mă-lā'shē-ă)
A disease characterized by a gradual softening and bending of the bones with varying severity of pain; softening occurs because the bones contain osteoid tissue which has failed to calcify due to lack of vitamin D or renal tubular dysfunction.
Synonym(s): adult rickets, late rickets.
[osteo- + G. malakia, softness]

os·te·o·ma·la·ci·a

(os'tē-ō-mă-lā'shē-ă)
Disease in adults characterized by a gradual softening and bending of bones with varying severity of pain.
Synonym(s): adult rickets.
[osteo- + G. malakia, softness]

rickets

a disease of young growing animals caused by a nutritional deficiency of phosphorus or vitamin D. There is a failure of calcification of osteoid and cartilage of the bones which become bowed and a persistence with enlargement of the epiphyses so that the joints appear swollen. The animals are lame and dentition is delayed. Radiological examination shows a wider and thicker growth plate.

adult rickets
osteomalacia; a rickets-like disease affecting adults.
fetal rickets
hypervitaminosis D rickets
deposition of large amounts of osteoid matrix in the metaphyses with a delay in its mineralization occurs in feeding excessive amounts of vitamin D.
inherited rickets
affected piglets are normal at birth but develop rickets indistinguishable from classical rickets. There is a defect in calcium absorption.
renal rickets
see renal secondary hyperparathyroidism.
vitamin D-resistant rickets
a condition almost indistinguishable from ordinary rickets clinically but resistant to unusually large doses of vitamin D; it is often familial but may occur sporadically. In hypophosphatemic vitamin D-resistant rickets, hypophosphatemia is the main characteristic, while in hypocalcemic vitamin D-resistant rickets, the serum concentration of phosphate is within normal limits or nearly so, and the concentration of calcium is abnormally low.
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