adult rhabdomyoma

adult rhabdomyoma

A rare, usually benign primary (extracardiac) striated muscle tumour (or tumours—multiple in 20% of cases) that arises in branchial arches III and IV of the head and neck (larynx, pharynx). It is more common in males > age 40.

Prognosis
May recur; 1:50 are malignant.
References in periodicals archive ?
In this article, we report a case of adult rhabdomyoma of the larynx that typified the common indolent progression of dysphagia and dysphonia but featured a more acute presentation of upper airway obstruction.
We report a case of adult rhabdomyoma of the larynx that features some of its typical and atypical presenting characteristics.
9) Adult rhabdomyoma occurs more frequently in men than women (4:1).
Adult rhabdomyomas have been confused with granular cell tumors during initial evaluation.
Crystal-storing histiocytosis associated with lymphoplasmacytic neoplasms: report of three cases mimicking adult rhabdomyoma.
33,34) Although CSH and adult rhabdomyoma are both composed of cells that contain eosinophic crystals and striations, they can be relatively easily separated on routine hematoxylin-eosinstained sections.
The differential diagnosis of a cardiac mass with features similar to CSH includes genetic storage disorders, adult rhabdomyoma, Weber-Christian disease, Langerhans cell histiocytosis, Rosai-Dorfman disease, Erdheim-Chester disease, or cardiac inflammatory myofibroblastic tumor.
Immunohistochemistry staining is positive for desmin and vimentin and is less dense for myoglobin than in adult rhabdomyoma.
Adult rhabdomyoma of the head and neck: A clinicopathologic and immunophenotypic study.
Adult rhabdomyomas are found almost exclusively in patients older than 40 years and occur in men three times more often than in women.
On gross pathology, adult rhabdomyomas are reddish-brown or gray, lobulated, and soft.
Some authors have speculated that extracardiac rhabdomyomas are hamartomas, but recent work by Gibas and Miettinen[11] showed a 15-19 translocation in a recurrent adult rhabdomyoma, making neoplastic transformation more likely.
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