adrenoreceptor


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adrenoreceptor

/adre·no·re·cep·tor/ (-re-sep´ter) adrenergic receptor.

ad·re·ner·gic re·cep·tors

(ad'rĕ-nĕr'jik rĕ-sep'tŏrz)
Reactive components of effector tissues, most of which are innervated by the sympathetic nervous system. Such receptors can be activated by norepinephrine, epinephrine, and adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles.
Synonym(s): adrenoreceptor.

ad·re·ner·gic re·cep·tors

(ad'rĕ-nĕr'jik rĕ-sep'tŏrz)
Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibers of the sympathetic nervous system. Such receptors can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs.
Synonym(s): adrenoceptor.

adrenoreceptor

a receptor essential to neurohumoral transmission, situated on or within the surface membranes of cells innervated by adrenergic neurons and in some cells which are not so innervated.
References in periodicals archive ?
Oxytocin increases locus coerruleus alpha 2 adrenoreceptor responsiveness in rats.
2) The action of one drug is prevented by a second drug acting on a separate part of the signalling pathway, eg verapamil prevents entry of calcium into myocardial cells and will counter the effects of dobutamine (a beta-1 adrenoreceptor agonist).
In humans, the mechanism of the latter was suggested to be the result of alpha-2 adrenoreceptor proliferation at the site of nerve damage and reduced transmission of nociceptive impulses and prevention or lessening of spinal cord sensitization when these receptors are activated.
The effects of the adrenoreceptor agonist phenylephrine and isoproterenol on the intracellular ion concentration of branchial ephitelial cells of brown trout (Salmo trutta L).
As highlighted below, delivering targeted ingredients directly into the skin has one key objective: to initiate lipolysis using a strategy that does not depend on beta-adrenoreceptor activation, since subcutaneous fat cells have a lower concentration of beta adrenoreceptors (which stimulate lipolysis) and a higher concentration of alpha adrenoreceptors (which inhibit lipolysis).
That observation, adds Bond, was an indication that blocking the receptor, scientifically known as beta-2 adrenoreceptor, might be a safer and more effective strategy for long-term asthma management than stimulating it.
Other hypothetical mechanisms could be ECG changes (such as QT-fnterval prolongation), pro coagulation effects, or direct effects on blood pressure via adrenoreceptor antagonism," the investigators noted.
Since we did not measure serum cortisol levels or the pituitary-adrenal axis function, we are unable to determine whether this had a significant role in altering adrenoreceptor expression.
The Foradil Aerolizer (formoterol inhalation powder), a long-acting, selective [beta]-2 adrenoreceptor agonist manufactured by Novartis Pharmaceuticals Corp.
Ephedrine is a direct agonist and an indirect adrenoreceptor agonist, causing release of noradrenaline from presynaptic sympathetic nerve terminals.
In this model, cardiotoxicity does not only occur via adrenoreceptor activation (22), but also ISO induces excessive production of free radicals resulting from oxidative metabolism of catecholamines and thus, the free radicals cause cell necrosis and contractile failure in the heart (23).
Pfizer will remain the market leader with its current blockbuster therapy, donepezil (Aricept), and the launch of its upcoming alpha adrenoreceptor antagonist, nicergoline (Sermion), expected to reach Europe and the U.