adrenocorticotrophin


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Related to adrenocorticotrophin: adrenocorticotropic hormone, adrenocorticotropin, Corticotropin releasing hormone

corticotropin

 [kor″tĭ-ko-tro´pin]
1. a hormone secreted by the anterior lobe of the pituitary gland that stimulates the cortex of the adrenal gland to secrete its hormones, including corticosterone. If production of corticotropin falls below normal, the adrenal cortex decreases in size, and production of the cortical hormones declines.
2. a pharmaceutical preparation of animal-derived corticotropin, administered intravenously for diagnostic testing of adrenocortical function and subcutaneously or intramuscularly, in a slowly absorbed gel form (repository corticotropin), as an anticonvulsant for treating infantile spasms. Called also adrenocorticotropic hormone (ACTH), adrenocorticotropin, and corticotrophin.

adrenocorticotrophin

/adre·no·cor·ti·co·troph·in/ (-kor″tĭko-tro´fin) corticotropin.

hormone

chemical substance that acts locally or is carried via blood to another body part, to cause a regulatory effect on functional activity or structure
  • adrenocorticotrophic hormone; ACTH; corticotrophin; adrenocorticotrophin anterior pituitary hormone stimulating release of glucocorticoid and mineralocorticoid and sex hormones (androgens) from cortex of adrenal gland; plasma ACTH levels are reduced in Cushing's syndrome (due to excess production of adrenal cortex hormones) and raised in Addison's disease (due to reduced adrenal cortex function)

  • antidiuretic hormone; ADH; vasopressin anterior pituitary hormone; causes urine concentration by increasing resorption of solute at the distal convoluted tubule of nephron; absence of ADH causes diabetes insipidus

  • follicle-stimulating hormone; FSH anterior pituitary hormone; acts on ovaries/testes to influence the release of the sex hormones (oestrogen/testosterone), and induce sperm growth/ovulation

  • growth hormone; GH; somatotropin anterior pituitary hormone; acts on many tissues, inducing normal growth

  • luteinizing hormone; LH anterior pituitary hormone; acts on ovaries/testes to influence sex hormone release (oestrogen/testosterone) and induce sperm growth/ovulation

adrenocorticotrophin

adrenocorticotropic hormone, or corticotropin.
References in periodicals archive ?
10-1131-01) was applied to measure insulin, and the radioactive immunoassay method (1470 Wizard-[gamma]-counter) was used to measure adrenocorticotrophin (ACTH) and cortisol.

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