adrenochrome


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adrenochrome

(ə-drē′nō-krōm′, -nə-)
n.
A substance formed by the oxidation of epinephrine.

Adrenochrome

A pigment which is generated in vivo from the oxidation of epinephrine, and allegedly linked to schizophrenia. This assertion formed the basis for the “disciplines” of orthomolecular medicine and orthomolecular psychiatry, which claim that schizophrenia, alcoholism, and other mental disorders can be managed by improved nutrition and megavitamin therapy. There is little peer-reviewed data to support the related hypotheses, which were championed by Abram Hoffer (1917–2009).

adrenochrome

(ă-drē′nŏ-krōm″) [ adreno- + Gr. chrōma, color]
C9H9NO3; a red pigment obtained by oxidation of epinephrine.
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References in periodicals archive ?
Increased oxidation will increase the formation of adrenochrome and other derivatives of the catecholamines.
Any factor that decreases the formation of adrenochrome will be therapeutic.
The adrenochrome hypothesis using adrenochrome as a member of a class of oxidized derivatives of the catecholamines, explains very economically a good deal of what is known about the schizophrenias.
He began in 1950 as director of psychiatric research at the department of public health in Saskatchewan where he and his colleagues developed the adrenochrome hypothesis of schizophrenia which is now, at last, being examined more seriously.
Why has the role of adrenochrome in schizophrenia been so neglected by mainstream medicine?
But the basic idea was extraordinarily sound and productive, leading to our adrenochrome hypothesis (Hoffer, Osmond, and Smythies 1954)
The amount of adrenochrome that can be formed must depend upon the amount of adrenalin that the body can make.
They are under extreme stress, and that is why it is only in that phase that they will make enough adrenochrome to cause the schizophrenic symptoms.
I suggest that it takes a minimum 5 hours' sleep out of 24 to be rid of excess adrenochrome and similar chrome indoles, and that it is wiser to be some distance from that minimum.
But when adrenochrome is treated with ascorbic acid under certain conditions, some of it is converted into 5,6-dihydroxy-N-methyl-indole, which was called leukoadrenochrome.
This was the protocol developed on the basis of the adrenochrome hypothesis.