adrenoceptor


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ad·re·ner·gic re·cep·tors

reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibers of the sympathetic nervous system. Such receptors can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs; receptor activation results in a change in effector tissue function, such as contraction of arteriolar muscles or relaxation of bronchial muscles; adrenergic receptors are divided into α-receptors and β-receptors, on the basis of their response to various adrenergic activating and blocking agents.

adrenoceptor

/adre·no·cep·tor/ (ah-dre″no-sep´ter) adrenergic receptor.adrenocep´tive

Adrenergic Receptor

Any of a family of G protein-coupled cell membrane receptors which receive neuronal impulses from postganglionic adrenergic fibres of the sympathetic nervous system, which are divided into:
(1) Alpha receptors, which evoke an excitatory response of smooth muscle cells to catecholamines. Alpha receptors are divided into alpha1 (Gq) and alpha2 (Gi) coupled receptors.
Selective agonist, alpha receptor Phenylephrine
Alpha receptor effects Vasoconstriction, reduced GI tract motility.
(2) Beta receptors, which dampen the response to catecholamines. Beta receptors are divided into beta1, beta2, beta3, which are linked to Gs, and adenylate cyclase, increasing cAMP, which in turn drives cAMP-dependent protein kinase that mediates intracellular events.
Selective agonist, beta receptor Isoprenaline
Beta receptor effects Increased cardiac output, increased renin secretion from juxtaglomerular cells, increased gastric ghrelin secretion, smooth muscle relaxation resulting in bronchodilation, reduced GI motility, relaxation of detrusor muscle of the bladder, lipolysis, glycogenolysis and gluconeogenesis, increased renin secretion, insulin secretion, vasodilation, anabolism and thermogenesis of skeletal muscle.

adrenoceptor

See BETA-ADRENOCEPTOR.

ad·re·ner·gic re·cep·tors

(ad'rĕ-nĕr'jik rĕ-sep'tŏrz)
Reactive components of effector tissues, most of which are innervated by adrenergic postganglionic fibers of the sympathetic nervous system. Such receptors can be activated by norepinephrine and/or epinephrine and by various adrenergic drugs.
Synonym(s): adrenoceptor.

adrenoceptor

see adrenergic receptors.
References in periodicals archive ?
For example, adrenoceptor alpha 1A, glutamate receptor ionotropic N-methyl D-aspartate 2A, and purinergic receptor P2X ligand-gated ion channel 4 in calcium signaling pathway, and glycine receptor alpha 1 and leptin receptor in neuroactive ligand-receptor interaction mediate actions in the nervous system through the binding of different neurotransmitters (Betz et al.
Animal and laboratory studies have suggested that alpha-2 adrenoceptor agonists like clonidine might block stress-related drug-seeking behavior, independently of their action as adjunctive medications during opioid detoxification.
The company's product portfolio includes alpha adrenoceptor agonist, analgesic, antipyretic, anti-inflammatory, anti-ulcer agents, antibiotics and stimulants, among others.
His thesis was in "A study on medetomidine an Alpha2 Adrenoceptor agent alone and in combination with other Anaesthetics on different animals.
His thesis was in "A study on medetomidine an Alpha-2 Adrenoceptor agent alone and in combination with other Anaesthetics on different animals.
Even for larger tumors, however, testing for pheochromocytoma remains important to ascertain the need for adrenoceptor blockade before surgery.
30) These findings supported the premise that stimulation of beta-adrenoceptors with adrenoceptor agonists before an elective CS may promote postnatal respiratory and metabolic adaptation.
Adrenoceptor polymorphisms and the risk of cardiac injury and dysfunction after subarachnoid hemorrhage.
To determine a possible mechanism of action of these plants, 45 extracts from Panamanian plants reported to have beneficial effects on the cardiovascular system were screened for their ability to bind to the [beta]1 adrenoceptor by competition binding assays with [.
Chronic Treatment with Beta Adrenoceptor Blockade on Exercise Performance, Haemodynamic and Metabolic Parameters in Healthy Men and Women.
There are three major groups of drugs currently used for wildlife capture: Alpha-2 adrenoceptor agonists, opioid agonists, and cyclohexanes (Kreeger et al.
This experiment examined the effects of the adrenoceptor antagonist yohimbine on risk assessment evoked by a novel odor.