The most common clinically observed side effects of adrenergic bronchodilators are tremor, tachycardia, tolerance to bronchodilator effect, loss of bronchoprotection, nervousness, worsening ventilation to perfusion ratio, hypokalemia, and sensitivity to additives and propellants.
Commonly reported side effects of the adrenergic bronchodilators include headache, nervousness, irritability, anxiety, and insomnia, which are caused by central nervous system stimulation.
Long-acting beta-2 adrenergic bronchodilators are used as maintenance medications taken daily on a scheduled basis to prevent acute bronchospastic events.
Corticosteroids are often found in combination with long-acting beta-2 adrenergic bronchodilators in inhaler devices (see Table 1).
Although theophylline is not as strong a bronchodilator as the adrenergic medications, it can be effective for some people--for example, patients with nighttime asthma--because its effects tend to last longer than the effects of adrenergic bronchodilators.
Often, using an inhaled adrenergic bronchodilator before exercise can prevent exercise-induced symptoms and allow people to be fully active.
The action of salmeterol in providing sustained protection from bronchoconstriction differs to a degree from that of the previously described adrenergic bronchodilators
The FDA has recently made several changes and additions to adrenergic bronchodilators
I will also discuss the benefits anticholingergic bronchodilators have when used in combination with adrenergic bronchodilators
In the last two issues I had discussed the use of short and long acting adrenergic bronchodilators.
The most common clinically observed side effects of adrenergic bronchodilators are tremor, tachycardia, tolerance to bronchodilator effect, loss of bron-choprotection, nervousness, worsening ventilation to perfusion ratio, hypokalemia, and sensitivity to additives and propellants.
This article will review long acting adrenergic bronchodilator
agents available and their indication for use.