Other findings included right and left ventricular dilatation, Pneumocystis pneumonia (Figure 1a), bilateral cytomegalovirus adrenalitis
, and an incidental appendiceal carcinoid tumor.
Other histopathologic findings were multifocal nonsuppurative hepatitis, adrenalitis
, and bronchointerstitial pneumonia.
Histopathologic examination of bird 1 identified typical lesions of PDD with a moderate multifocal encephalitis (Fig 1) and mild myocarditis, adrenalitis
, and ganglioneuritis of the intestine.
Lymphoid hypophysitis in a patientwith lymphoid thyroiditis, lymphoid adrenalitis
, and idiopathic retroperitoneal fibrosis.
One of these patients with Type 1 diabetes mellitus has developed generalized MG, Addisonian pernicious anaemia, adrenalitis
and thyroiditis which did not fit into the Type 1 or Type 2 classical polyendocrine deficiency syndromes (11).
Dogs 1 and 3 had multifocal pancreatitis and adrenalitis
The most commonly recognised manifestation of CMV is CMV retinitis (CMV-R), but pneumonitis, colitis, oesophagitis, adrenalitis
, and neurological involvement are also described.
Cytomegalovirus pneumonitis, Pneumocystis jiroveci (carinii) pneumonia, cytomegalovirus adrenalitis
, and disseminated toxoplasmosis were identified microscopically, and pulmonary cytomegalovirus was confirmed postmortem by viral culture of the lung tissue.
The bird also had adrenalitis
, encephalitis, and neuritis, as well as a myocarditis.
The dolphin also exhibited nonsuppurative meningoencephalitis, bronchointerstitial pneumonia, necrotizing hepatitis, and necrotizing adrenalitis
associated with Toxoplasma spp.
Virus antigen expression was detected in multiple foci of medullary and cortical cells of the adrenal gland (online Appendix Figure 4, panel C) and was associated with necrotizing adrenalitis
(online Appendix Figure 4, panel D).
Other common lesions included necrotizing pancreatitis (Figure 2D) and adrenalitis
(Figure 2C) and multifocal myocardial necrosis.